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Fig. 7 | BMC Infectious Diseases

Fig. 7

From: TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients

Fig. 7

TLR9 1486CC genotype is associated with lower CD4 counts and higher CD8 immune activation and plasma IP10 levels in HIV infected individuals. TLR91486 polymorphism was determined by PCR-RFLP analysis. Plasma IP10 levels were determined via quantitative ELISA. Differences between TLR9 1486CC and CT/TT genotypes with respect to (a) CD4 counts and (b) CD8 immune activation is shown. (c) Comparison of CD8 immune activation between TLR9 1486 CC, CT or TT genotypes. (d) Plasma IP10 levels between TLR9 1486CC or CT/TT genotype groups. One tailed student’s t-test or Kruskal-Wallis test was used for statistical analysis

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BMC Infectious Diseases

ISSN: 1471-2334

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