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Table 1 Variations in extracellular hydrolytic activities in Candida albicans isolates exposed to antifungal sub-MICs

From: Influence of subinhibitory antifungal concentrations on extracellular hydrolases and biofilm production by Candida albicans recovered from Egyptian patients

Virulence factor Control NYS FLU MCF
Phospholipase (PZ) Median 1.0650 1.0176 1.0282 1.0251
Range 1.0000–1.2634 1.0000–1.2152 1.0000–1.1944 1.0000–1.2347
% Reduction − 4.45% − 3.46% − 3.75%
p-value   0.010 0.047 0.022
Aspartyl protease (Prz) Median 1.2628 1.0556 1.0654 1.0580
Range 1.0000–1.8000 1.000–1.2000 1.0000–1.2667 1.0000–1.3333
% Reduction −16.41% −15.63% −16.22%
p-value   0.001 0.007 0.003
Haemolysin (HZ) Median 1.6814 1.4736 1.4519 1.4272
Range 1.4296–2.0000 1.1667–1.8750 1.1574–1.8571 1.1309–1.8571
% Reduction −12.36% −13.65% −15.12%
p-value*   < 0.001 < 0.001 < 0.001
  1. *p-values of less than 0.05 (in bold) were counted statistically significant
  2. NYS Nystatin, FLU Fluconazole, MCF Micafungin