Table 1 Variations in extracellular hydrolytic activities in Candida albicans isolates exposed to antifungal sub-MICs

Phospholipase (P_Z)

Median

1.0650

1.0176

1.0282

1.0251

Range

1.0000–1.2634

1.0000–1.2152

1.0000–1.1944

1.0000–1.2347

% Reduction

–

− 4.45%

− 3.46%

− 3.75%

p-value

0.010

0.047

0.022

Aspartyl protease (Pr_z)

Median

1.2628

1.0556

1.0654

1.0580

Range

1.0000–1.8000

1.000–1.2000

1.0000–1.2667

1.0000–1.3333

% Reduction

–

−16.41%

−15.63%

−16.22%

p-value

0.001

0.007

0.003

Haemolysin (H_Z)

Median

1.6814

1.4736

1.4519

1.4272

Range

1.4296–2.0000

1.1667–1.8750

1.1574–1.8571

1.1309–1.8571

% Reduction

–

−12.36%

−13.65%

−15.12%

p-value*

< 0.001

< 0.001

< 0.001