|
variables
|
Adjusted HR with model 1a
|
p value
|
Adjusted HR with model 2b
|
p value
|
|---|
|
Neutropenia
|
0.74
|
0.647
| | |
|
treatment periodc
|
|
before construction (phase A)
|
1.32
|
0.698
|
1.21
|
0.790
|
|
during construction (phase B)
|
2.75
|
0.163
|
2.82
|
0.140
|
|
the late period after moving (phase D)
|
4.63
|
0.010
|
4.64
|
0.008
|
|
antifungal prophylaxisd
|
1.40
|
0.702
|
1.41
|
0.430
|
|
ALL vs AML
|
0.59
|
0.423
|
0.62
|
0.470
|
|
age
|
1.19
|
0.717
|
1.23
|
0.660
|
- AML denotes acute myelogenous leukemia; ALL acute lymphoblastic leukemia, HR hazard ratio
- aModel 1 is a Cox proportional hazards ratio with time-dependent covariates
- bModel 2 is a Fine and Gray proportional hazard regression model
- cHR is calculated by comparison of the incidence in each period with in the early period after moving
- dHR is the ratio of the incidence in patients who received fluconazole with mold-active agent prophylaxis with the incidence in patients who received fluconazole-only prophylaxis
