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Table 2 Serotypes of S. pneumoniae isolates producing biofilm, isolated alone or with H. influenzae

From: Biofilm production by Haemophilus influenzae and Streptococcus pneumoniae isolated from the nasopharynx of children with acute otitis media

  

S. pneumoniae

H. influenzae

Biofilm production by either S. pneumoniae or H. influenzae isolated together

 

Biofilm production by S. pneumoniae Total

Biofilm production by S. pneumoniae isolated alone

Biofilm production by S. pneumoniae isolated with H. influenzae

Biofilm production by H. influenzae isolated with S. pneumoniae

   

S. pneumoniae Total

S. pneumoniae Biofilm+

S. pneumoniae Biofilm -

  

Serotype (n)

n (%)

n (%)

Biofilm + n (%)

Hi Biofilm +

Hi Biofilm -

Hi Biofilm +

Hi Biofilm -

n (%)

n (%)

PCV7

 6B (11)

10 (91)

7/8 (88)

3/3 (100)

1

2

  

1/3(33)

3/3 (100)

 9 V (2)

2 (100)

1/1 (100)

1/1 (100)

1

   

1/1 (100)

1/1 (100)

 14 (10)

6(60)

1/2 (50)

5/8 (63)

5

 

3

 

8/8 (100)

8/8 (100)

 18C (1)

1 (100)

0

1/1 (100)

1

   

1/1 (100)

1/1 (100)

 19F (17)

7 (41)

2/6 (33)

5/11 (45)

4

1

4

2

8/11 (73)

9/11 (82)

 23F (13)

5 (38)

3 /7(43)

2/5 (40)

1

1

2

1

3/5 (60)

4/5 (80)

Total

31/54 (57.4)

14/24 (58.3)

17/29 (58.6)

13

4

9

3

22/29 (75.9)

26/29 (89.9)

PCV13 additional serotypes

 1 (1)

0

0

0/1

  

1

 

1/1 (100)

1/1(100)

 3 (1)

0

0/1

0/0

    

0

0

 5 (1)

1 (100)

0

1/1 (100)

 

1

  

0/1

1/1 (100)

 6A (6)

3 (50)

2/5 (40)

1/1 (100)

1

   

1/1(100)

1/1 (100)

 7F (2)

2 (100)

1/1 (100)

1/1 (100)

1

   

1/1(100)

1/1 (100)

 19A (17)

16 (94)

8/8 (100)

8/9 (89)

6

2

1

 

7/9 (78)

9/9 (100)

Total

22/28 (78.5)

11/15 (73.3)

11/13(84)

8

3

2

 

10/13 (77)

13/13 (100)

Other serotypes

 15B/C (15)

14 (93)

8/8 (100)

6/7 (86)

4

2

 

1

4/7 (57)

6/7 (86)

 15A (12)

6 (50)

3/5 (60)

3/7 (43)

3

 

4

 

7/7 (100)

7/7 (100)

 11A (9)

6 (67)

3/3 (100)

3/6 (50)

3

 

2

1

5/6 (83)

5/6 (83)

 23B (9)

3 (33)

0/4

3/5 (60)

3

 

2

 

5/5 (100)

5/5 (100)

 23A (12)

8 (67)

6/8 (75)

2/4 (50)

1

1

2

 

2/3 (67)

4/4 (100)

 10A (6)

3 (50)

0/2

3/4 (75)

1

2

1

 

2/3 (67)

4/4 (100)

 21 (5)

2 (40)

1/2 (50)

1/3 (33)

 

1

2

 

2/3(67)

3/3 (100)

 35F (4)

4 (100)

1/1 (100)

3/3 (100)

2

1

  

2/3 (67)

3/3 (100)

 35B (6)

5 (83)

3/4 (75)

2/2 (100)

 

2

  

0/2

2/2 (100)

 6C (4)

2 (50)

1/2 (50)

1/2 (50)

1

 

1

 

2/2 (100)

2/2 (100)

 17F (4)

4 (100)

3/3 (100)

1/1 (100)

1

   

1/1(100)

1/1 (100)

 22F(2), 29(2)

2 (50)

0/2

2/2 (100)

1

   

2/2 (100)

2/2(100)

 24F (2)

1 (50)

1/1 (100)

0/1

   

1

0/1

0

 15F (1)

0 (0)

0/1 (0)

0/1

  

1

 

1/1 (100)

1/1 (100)

 16(1)

1 (100)

0

1/1 (100)

1

   

1/1 (100)

1/1 (100)

 38 (1)

1 (100)

0

1/1 (100)

 

1

  

0/1

1/ 1(100)

 8(2), 12F (1), 25A (1) 31 (1), 33F (1)

5 (83.3)

5/6 (83.3)

0/0

    

0

0

Total

67/101 (69.3)

43/62 (69.3)

36/57 (63.1)

24

11

17

4

36/48 (75)

46/48 (94.6)

NT (7)

7 (100)

3/3(100)

4/4 (100)

3

1

  

3/4 (75)

4/4 (100)

Total

127/190 (66.8%)

64/95 (67.4%)

64/97 (66%)

46/65 (71%)

18/65 (27.6%)

26/32 (81.2%)

6/32 (18.7%)

71/94 (75.5%)

89/94 (94.6%)

  1. PCV7: Serotypes included in the PCV7 vaccin
  2. PCV13 additionnal serotypes: Additionnal serotypes added in the PCV13 vaccin
  3. NT: non typable serotypes