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Table 2 Serotypes of S. pneumoniae isolates producing biofilm, isolated alone or with H. influenzae

From: Biofilm production by Haemophilus influenzae and Streptococcus pneumoniae isolated from the nasopharynx of children with acute otitis media

   S. pneumoniae H. influenzae Biofilm production by either S. pneumoniae or H. influenzae isolated together
  Biofilm production by S. pneumoniae Total Biofilm production by S. pneumoniae isolated alone Biofilm production by S. pneumoniae isolated with H. influenzae Biofilm production by H. influenzae isolated with S. pneumoniae
    S. pneumoniae Total S. pneumoniae Biofilm+ S. pneumoniae Biofilm -   
Serotype (n) n (%) n (%) Biofilm + n (%) Hi Biofilm + Hi Biofilm - Hi Biofilm + Hi Biofilm - n (%) n (%)
PCV7
 6B (11) 10 (91) 7/8 (88) 3/3 (100) 1 2    1/3(33) 3/3 (100)
 9 V (2) 2 (100) 1/1 (100) 1/1 (100) 1     1/1 (100) 1/1 (100)
 14 (10) 6(60) 1/2 (50) 5/8 (63) 5   3   8/8 (100) 8/8 (100)
 18C (1) 1 (100) 0 1/1 (100) 1     1/1 (100) 1/1 (100)
 19F (17) 7 (41) 2/6 (33) 5/11 (45) 4 1 4 2 8/11 (73) 9/11 (82)
 23F (13) 5 (38) 3 /7(43) 2/5 (40) 1 1 2 1 3/5 (60) 4/5 (80)
Total 31/54 (57.4) 14/24 (58.3) 17/29 (58.6) 13 4 9 3 22/29 (75.9) 26/29 (89.9)
PCV13 additional serotypes
 1 (1) 0 0 0/1    1   1/1 (100) 1/1(100)
 3 (1) 0 0/1 0/0      0 0
 5 (1) 1 (100) 0 1/1 (100)   1    0/1 1/1 (100)
 6A (6) 3 (50) 2/5 (40) 1/1 (100) 1     1/1(100) 1/1 (100)
 7F (2) 2 (100) 1/1 (100) 1/1 (100) 1     1/1(100) 1/1 (100)
 19A (17) 16 (94) 8/8 (100) 8/9 (89) 6 2 1   7/9 (78) 9/9 (100)
Total 22/28 (78.5) 11/15 (73.3) 11/13(84) 8 3 2   10/13 (77) 13/13 (100)
Other serotypes
 15B/C (15) 14 (93) 8/8 (100) 6/7 (86) 4 2   1 4/7 (57) 6/7 (86)
 15A (12) 6 (50) 3/5 (60) 3/7 (43) 3   4   7/7 (100) 7/7 (100)
 11A (9) 6 (67) 3/3 (100) 3/6 (50) 3   2 1 5/6 (83) 5/6 (83)
 23B (9) 3 (33) 0/4 3/5 (60) 3   2   5/5 (100) 5/5 (100)
 23A (12) 8 (67) 6/8 (75) 2/4 (50) 1 1 2   2/3 (67) 4/4 (100)
 10A (6) 3 (50) 0/2 3/4 (75) 1 2 1   2/3 (67) 4/4 (100)
 21 (5) 2 (40) 1/2 (50) 1/3 (33)   1 2   2/3(67) 3/3 (100)
 35F (4) 4 (100) 1/1 (100) 3/3 (100) 2 1    2/3 (67) 3/3 (100)
 35B (6) 5 (83) 3/4 (75) 2/2 (100)   2    0/2 2/2 (100)
 6C (4) 2 (50) 1/2 (50) 1/2 (50) 1   1   2/2 (100) 2/2 (100)
 17F (4) 4 (100) 3/3 (100) 1/1 (100) 1     1/1(100) 1/1 (100)
 22F(2), 29(2) 2 (50) 0/2 2/2 (100) 1     2/2 (100) 2/2(100)
 24F (2) 1 (50) 1/1 (100) 0/1     1 0/1 0
 15F (1) 0 (0) 0/1 (0) 0/1    1   1/1 (100) 1/1 (100)
 16(1) 1 (100) 0 1/1 (100) 1     1/1 (100) 1/1 (100)
 38 (1) 1 (100) 0 1/1 (100)   1    0/1 1/ 1(100)
 8(2), 12F (1), 25A (1) 31 (1), 33F (1) 5 (83.3) 5/6 (83.3) 0/0      0 0
Total 67/101 (69.3) 43/62 (69.3) 36/57 (63.1) 24 11 17 4 36/48 (75) 46/48 (94.6)
NT (7) 7 (100) 3/3(100) 4/4 (100) 3 1    3/4 (75) 4/4 (100)
Total 127/190 (66.8%) 64/95 (67.4%) 64/97 (66%) 46/65 (71%) 18/65 (27.6%) 26/32 (81.2%) 6/32 (18.7%) 71/94 (75.5%) 89/94 (94.6%)
  1. PCV7: Serotypes included in the PCV7 vaccin
  2. PCV13 additionnal serotypes: Additionnal serotypes added in the PCV13 vaccin
  3. NT: non typable serotypes