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Table 1 Demographic and clinical characteristic of children with HAdV-3 and HAdV-7 of admission, 2009-2015

From: Human adenovirus type 7 infection causes a more severe disease than type 3

Characteristic HAdV-3 HAdV-7 p
(n = 127) (n = 131)
Age(years)
  ≤ 2 years 91 (71.7) 83 (63.4) 0.155
  > 2 years 36 (28.3) 48 (36.6)  
Gender
 Male/female 85/42 90/41 0.761
 Underlying diseases 26 (20.5) 24 (18.3) 0.753
 Coinfection 73 (57.5) 53 (40.5) 0.851
Symptom, signs
 Cough 118 (92.9) 124 (94.7) 0.974
 Fever 89 (70.1) 112 (85.5) 0.656
 Peak temperature (>  39) 27 (21.3) 25 (19.1) 0.953
 Wheezing 50 (39.4) 89 (32.1) 0.220
 Croup 50 (39.4) 42 (32.1) 0.681
 Dyspnea 19 (15.0) 31 (23.7) 0.077
 Dry rales 57 (44.9) 53 (40.5) 0.627
 Moist rales 87 (68.5) 101 (77.1) 0.763
 Seizure 1 (0.8) 2 (1.5) 1.000
Diagnosis
 PCF 1 (0.8) 1 (0.8) 1.000
 URTI 3 (2.4) 3 (2.3) 1.000
 Bronchitis 2 (1.6) 6 (4.6) 0.279
 Pneumonia 121 (95.3) 121 (92.4) 0.958
Complication
 Pleural effusion 2 (1.6) 6 (4.6) 0.279
 Severe pneumonia 21 (16.5) 41 (31.3) 0.005a
 Respiratory failure 19 (15.0) 36 (27.5) 0.015a
 ARDS 0 1 (0.8) 1.000
 Suspicious BO 1 (0.8) 2 (1.5) 1.000
 Intracranial infection 1 (0.8) 4 (3.1) 0.369
 Toxic encephalopathy 1 (0.8) 25 (19.1) 0.0001a
Outcomes
 Hospitalization days 7.7 ± 0.7 8.2 ± 0.6 0.031a
 ICU admission 2 (1.6) 6 (4.6) 0.279
  1. Note: Underlining diseases include premature birth, congenital heart disease, asthma, eczema and tuberculosis
  2. Coinfection with influenza viruses, RSV, PIV, MPV, HRV, COV and HBoV
  3. The numbers in brackets represent the percentage of positive cases
  4. Bold Abbreviations: PCF pharyngo conjunctival fever, URTI upper respiratory tract infection, ICU intensive care unit, BO Bronchiolitis obliterans, not determined, ARDS acute respiratory distress syndrome
  5. P-values indicate comparisons with significance differences (P ≤ 0.05)
  6. a”: a significant difference between two groups