From: Mortality in hospitalized patients with tuberculous meningitis
Surviving (n = 183) | Deceased (n = 80) | Bivariable Analysis | Multivariable Analysis | |||||
---|---|---|---|---|---|---|---|---|
RR | 95% CI | p | RR | 95% CI | p | |||
Male | 134 (73.2%) | 57 (71.2%) | 0.93 | 0.63–1.40 | 0.740 | 0.79 | 0.54–1.13 | 0.201 |
Age > 40 years old | 53 (28.9%) | 36 (45%) | 1.59 | 1.12–2.29 | 0.010 | 1.64 | 1.16–2.29 | 0.004 |
HIV Infection | 58 (31.7%) | 42 (52.5%) | 1.80 | 1.25–2.60 | 0.001 | 2.06 | 1.44–2.94 | < 0.001 |
History of tuberculosis | 40 (21.9%) | 23 (28.8%) | 1.28 | 0.84–1.90 | 0.217 | |||
Alcoholism / Drug addiction | 40 (21.9%) | 20 (25.0%) | 1.13 | 0.74–1.71 | 0.572 | |||
Glasgow < 14 | 86 (48.9%) | 60 (77.3%) | 2.30 | 1.58–3.48 | < 0.001 | 2.08 | 1.38–2.75 | < 0.001 |
Focal Neurologic deficits | 56 (31.8%) | 35 (45.5%) | 1.48 | 1.03–2.14 | 0.036 | 1.14 | 0.79–1.64 | 0.473 |
BMRC II | 90 (49.2%) | 43 (53.8%) | 1.88 | 1.13–3.13 | 0.015 | 1.78 | 1.07–2.97 | 0.027 |
BMRC III | 16 (8.74%) | 21 (26.3%) | 3.30 | 1.94–5.59 | < 0.001 | 3.11 | 1.78–5.45 | < 0.001 |
ADA > 9 UI/L | 87 (51.8%) | 43 (57.3%) | 1.17 | 0.80–1.71 | 0.426 | |||
MDR-TB | 4 (16.7%) | 4 (20.0%) | 1.08 | 0.50–2.39 | 0.833 | |||
CSF Positive culture | 34 (18.6%) | 34 (42.5%) | 2.11 | 1.50–3.00 | < 0.001 | 1.95 | 1.38–2.75 | < 0.001 |
Tuberculosis outside CNS | 53 (39.3%) | 22 (52.3%) | 1.43 | 0.95–2.15 | 0.086 |