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Table 4 Factors associated with death during hospitalization

From: Mortality in hospitalized patients with tuberculous meningitis

 

Surviving (n = 183)

Deceased (n = 80)

Bivariable Analysis

Multivariable Analysis

RR

95% CI

p

RR

95% CI

p

Male

134 (73.2%)

57 (71.2%)

0.93

0.63–1.40

0.740

0.79

0.54–1.13

0.201

Age > 40 years old

53 (28.9%)

36 (45%)

1.59

1.12–2.29

0.010

1.64

1.16–2.29

0.004

HIV Infection

58 (31.7%)

42 (52.5%)

1.80

1.25–2.60

0.001

2.06

1.44–2.94

< 0.001

History of tuberculosis

40 (21.9%)

23 (28.8%)

1.28

0.84–1.90

0.217

   

Alcoholism / Drug addiction

40 (21.9%)

20 (25.0%)

1.13

0.74–1.71

0.572

   

Glasgow < 14

86 (48.9%)

60 (77.3%)

2.30

1.58–3.48

< 0.001

2.08

1.38–2.75

< 0.001

Focal Neurologic deficits

56 (31.8%)

35 (45.5%)

1.48

1.03–2.14

0.036

1.14

0.79–1.64

0.473

BMRC II

90 (49.2%)

43 (53.8%)

1.88

1.13–3.13

0.015

1.78

1.07–2.97

0.027

BMRC III

16 (8.74%)

21 (26.3%)

3.30

1.94–5.59

< 0.001

3.11

1.78–5.45

< 0.001

ADA > 9 UI/L

87 (51.8%)

43 (57.3%)

1.17

0.80–1.71

0.426

   

MDR-TB

4 (16.7%)

4 (20.0%)

1.08

0.50–2.39

0.833

   

CSF Positive culture

34 (18.6%)

34 (42.5%)

2.11

1.50–3.00

< 0.001

1.95

1.38–2.75

< 0.001

Tuberculosis outside CNS

53 (39.3%)

22 (52.3%)

1.43

0.95–2.15

0.086