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Table 1 Characteristics associated with mortality during tuberculosis treatment

From: Development and validation of a risk score to predict mortality during TB treatment in patients with TB-diabetes comorbidity

  Total Completed Deceased Unadjusted OR Adjusted OR Adjusted p
(N = 1227) (n = 1115) (n = 112) (95% CI) (95% CI)  
Age ≥ 65 (years) 322 (26.2) 260 (23.3) 62 (55.4) 4.08 (2.74, 6.07) 4.85 (3.00, 7.85) < 0.001
Male gender 790 (64.4) 712 (63.9) 78 (69.6) 1.30 (0.85, 1.98)   
Race/Ethnicity
 White 90 (7.3) 78 (7.0) 12 (10.7) 1.80 (0.93, 3.48)   
 Black 136 (11.1) 119 (10.7) 17 (15.2) 1.67 (0.95, 2.95)   
 Hispanic 827 (67.4) 762 (68.3) 65 (58.0) (reference   
 Asian 164 (13.4) 147 (13.2) 17 (15.2) 1.36 (0.77, 2.38)   
 Other 10 (0.8) 9 (0.8) 1 (0.9) 1.30 (0.16, 10.44)   
US-born 450 (40.0) 396 (38.7) 54 (51.9) 1.70 (1.14, 2.50) 1.64 (1.03, 2.62) 0.04
Homeless 41 (3.3) 33 (3.0) 8 (7.1) 2.52 (1.14, 5.60) 2.88 (1.05, 7.88) 0.04
Inmate in a correctional institution 35 (3.3) 33 (3.4) 2 (2.1) 0.61 (0.14, 2.58)   
Resident of long-term care facility 21 (1.7) 14 (1.3) 7 (6.3) 5.24 (2.07, 13.28) 1.50 (0.49, 4.58) 0.47
IDU addicts 15 (1.2) 10 (0.9) 5 (4.5) 5.16 (1.73, 15.38) 7.25 (1.64, 31.98) 0.01
Non-IDU addicts 73 (5.9) 64 (5.7) 9 (8.0) 1.43 (0.69, 2.97)   
Excessive alcohol consumption 182 (14.8) 174 (15.6) 8 (7.1) 0.42 (0.20, 0.87) 0.46 (0.20, 1.07) 0.07
Organ transplant receiver 8 (0.7) 7 (0.6) 1 (0.9) 1.43 (0.17, 11.70)   
Chronic kidney failure 60 (4.9) 38 (3.4) 22 (19.6) 6.93 (3.93, 12.22) 7.00 (3.59, 13.62) < 0.001
Immunosuppression (medical condition or medication) 35 (2.9) 30 (2.7) 5 (4.5) 1.69 (0.64, 4.45)   
Pulmonary TB 1110 (90.5) 1011 (90.7) 99 (88.4) 0.78 (0.42, 1.45)   
TB meningitis 10 (0.8) 7 (0.6) 3 (2.7) 4.36 (1.11, 17.09) 7.25 (1.54, 34.08) 0.01
Miliary TB 33 (2.7) 25 (2.3) 8 (7.1) 3.32 (1.46, 7.55) 3.79 (1.41, 10.21) 0.01
TB-CXR 1084 (88.3) 983 (88.2) 101 (90.2) 1.23 (0.64, 2.36)   
Cavitation on CXR 509 (47.0) 479 (48.7) 30 (29.7) 0.44 (0.28, 0.69) 0.69 (0.41, 1.15) 0.15
AFB smear (+) 684 (61.4) 636 (61.6) 48 (58.5) 0.88 (0.56, 1.39) 1.74 (1.01, 2.98) 0.04
Culture (+) 863 (70.3) 799 (71.7) 64 (57.1) 2.52 (1.73, 3.68)   
TB case verified by positive culture, NAA, or AFB smear 1066 (86.9) 964 (86.5) 102 (91.1) 1.60 (0.82, 3.13)   
HIV status (+) 23 (1.9) 15 (1.3) 8 (7.1) 7.40 (3.04, 18.03) 11.07 (3.66, 33.46) < 0.001
MDR-TB 10 (0.8) 8 (0.7) 2 (1.8) 2.42 (0.51, 11.54)   
Mtb East Asian lineage 128 (13.2) 114 (13.0) 14 (15.2) 1.20 (0.66, 2.20)   
  1. CXR chest radiograph, TB-CXR abnormalities on CXR consistent with tuberculosis, MDR-TB Multi-drug resistant TB, NAA Nucleic Acid Amplification; Excessive alcohol consumption, excessive alcohol consumption in the past 12 months; Mtb, Mycobacterium tuberculosis