Skip to main content

Table 4 Univariate and fitted estimates of covariates included in the time-dependent Cox proportional hazard models on the risk of blood stream infection and mortality, including variables confined by the modified comorbidity index

From: Risk of death after first-time blood stream infection in incident dialysis patients with specific consideration on vascular access and comorbidity

Model entry Variable Univariate HR P Value Fitted HR P value Univariate HR P Value Fitted HR P Value
   Blood stream infection Mortality
RRT initiation AVF* 1.29 0.016 1.37 0.003 0.97 0.745 0.90 0.223***
TC* 2.29 < 0.001 2.25 < 0.001 1.75 < 0.001 1.48 < 0.001
NTC* 7.53 < 0.001 6.92 < 0.001 6.20 < 0.001 5.19 < 0.001
Sex 1.06 NS – – 0.98 NS – –
Age 50–59** 1.14 NS – – 1.75 0.001 1.65 0.004
Age 60–69** 1.05 NS – – 2.56 < 0.001 2.20 < 0.001
Age > 70** 1.01 NS – – 4.77 < 0.001 3.70 < 0.001
Heart Failure 1.30 0.003 – – 2.05 < 0.001 1.34 < 0.001
AMI 1.20 0.068 – – 1.92 < 0.001 1.23 0.013
Vascular 1.13 NS – – 1.78 < 0.001 1.25 0.002
CNS disease 0.96 NS – – 1.45 < 0.001 1.14 0.079
COPD 1.18 0.094 – – 1.79 < 0.001 1.34 < 0.001
Collagenoses 0.98 NS – – 1.02 NS 0.84 0.122
Peptic ulcer 1.25 0.039 – – 1.48 < 0.001 – –
Liver disease 1.76 < 0.001 1.52 0.005 1.36 0.028 1.41 0.016
Cancer 1.18 0.072 – – 1.81 < 0.001 1.35 < 0.001
Diabetes 1.34 < 0.001 1.30 < 0.001 1.30 < 0.001 1.22 0.003
Post BSI AVF* 1.14 0.720 0.98 0.947 0.76 0.252 0.88 0.627 ***
TC* 2.38 0.025 1.67 0.195 1.25 0.416 1.66 0.086
NTC* 3.86 0.002 2.36 0.022 3.19 < 0.001 3.58 < 0.001
Sex 1.13 NS – – 1.30 0.037 – –
Age 50–59** 1.57 0.096 – – 1.49 NS 1.70 0.093
Age 60–69** 1.26 NS – – 2.66 < 0.001 2.81 < 0.001
Age > 70** 1.50 NS – – 6.13 < 0.001 6.11 < 0.001
Heart Failure 1.54 0.020 – – 1.82 < 0.001 1.43 0.010
AMI 1.40 NS – – 1.80 < 0.001 – –
Vascular 1.11 NS – – 1.71 < 0.001 – –
CNS disease 1.11 NS – – 1.43 0.008 – –
COPD 1.07 NS – – 1.25 NS – –
Collagenosis 1.98 0.003 1.58 0.050 0.78 NS – –
Peptic ulcer 2.00 < 0.001 1.73 0.005 1.43 0.017 – –
Liver disease 1.94 0.007 1.82 0.021 1.39 NS 2.23 < 0.001
Cancer 1.62 0.009 1.36 0.115 2.30 < 0.001 1.64 < 0.001
Diabetes 1.44 0.019 1.46 0.024 0.97 NS – –
Gram pos 0.84 NS – – 0.68 0.003 0.80 0.100
  1. AMI acute myocardial infarction, CNS central nerve system, COPD chronic obstructive pulmonary disease, HD hemodialysis, AVF arteriovenous fistula, TC tunneled catheter, NTC non-tunneled catheter, NS not significant, HR hazard ratio, CI confidence interval
  2. *Analyzed as a four-leveled variable with peritoneal dialysis as reference
  3. **Analyzed as a four-leveled variable with ‘age < 50 years’ as reference
  4. ***Included in the model as the overall P-value for the four-leveled variable was < 0.15
  5. - did not meet the significance levels for final assessments in the fitted models
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us