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Table 3 Risk of blood stream infections and mortality associated with covariates included in the time-dependent cox proportional hazard models

From: Risk of death after first-time blood stream infection in incident dialysis patients with specific consideration on vascular access and comorbidity

Model entry

variable

HR (CI)

P value

HR (CI)

P value

  

Blood stream infection

Mortality

RRT initiation

AVFa

1.35 (1.20–1.67)

0.005

0.86 (0.72–1.03)

NS

TCa

2.25 (1.74–2.90)

< 0.001

1.42 (1.14–1.77)

0.002

NTCa

6.87(5.53-8.48)

< 0.001

5.22 (4.36–6.25)

< 0.001

Sex

1.10 (0.95–1.23)

NS

1.02 (0.89–1.16)

NS

Age 50–59b

1.19 (0.92–1.54)

NS

1.55 (1.10–2.18)

0.012

Age 60–69b

1.05 (0.83–1.32)

NS

2.14 (1.59–2.90)

< 0.001

Age > 70b

0.91 (0.73–1.13)

NS

3.71 (2.79–4.93)

< 0.001

MCCI (2, 3)c

0.87 (0.71–1.08)

NS

1.75 (1.36–2.24)

< 0.001

MCCI (>  3)c

1.14 (0.94–1.40)

NS

2.76 (2.18–3.51)

< 0.001

Post BSI

AVFa

0.94 (0.46–1.93)

NS

0.83 (0.50–1.39)

NS

TCa

1.68 (0.77–3.70)

NS

1.30 (0.72–2.34)

NS

NTCa

2.29 (1.09–4.82)

0.030

3.20 (1.86–5.50)

< 0.001

Sex

1.14 (0.81–1.60)

NS

1.07 (0.83–1.38)

NS

Age 50–59b

1.47 (0.85–2.56)

NS

1.53 (0.82–2.86)

NS

Age 60–69b

1.25 (0.75–2.10)

NS

2.56 (1.50–4.37)

< 0.001

Age > 70c

1.35 (0.81–2.23)

NS

5.41 (3.26–9.00)

< 0.001

MCCI (2, 3)c

1.70 (0.94–3.07)

0.081

1.96 (1.20–3.20)

0.008

MCCI (>  3)c

2.99 (1.72–5.19)

< 0.001

2.99 (1.88–4.74)

< 0.001

Gram +

0.89 (0.62–1.27)

NS

0.77 (0.59–0.99)

0.044

  1. HD hemodialysis, AVF arteriovenous fistula, TC tunneled catheter, NTC non-tunneled catheter, MCCI modified Charlson comorbidity index, NS not significant, HR hazard ratio, CI confidence interval
  2. a Analyzed as a four-leveled variable with peritoneal dialysis as reference
  3. b Analyzed as a four-leveled variable with ‘age < 50 years’ as reference
  4. c Analyzed as a three-leveled variable with ‘MCCI = 1’ as reference