Skip to main content

Table 3 Risk of blood stream infections and mortality associated with covariates included in the time-dependent cox proportional hazard models

From: Risk of death after first-time blood stream infection in incident dialysis patients with specific consideration on vascular access and comorbidity

Model entry variable HR (CI) P value HR (CI) P value
   Blood stream infection Mortality
RRT initiation AVFa 1.35 (1.20–1.67) 0.005 0.86 (0.72–1.03) NS
TCa 2.25 (1.74–2.90) < 0.001 1.42 (1.14–1.77) 0.002
NTCa 6.87(5.53-8.48) < 0.001 5.22 (4.36–6.25) < 0.001
Sex 1.10 (0.95–1.23) NS 1.02 (0.89–1.16) NS
Age 50–59b 1.19 (0.92–1.54) NS 1.55 (1.10–2.18) 0.012
Age 60–69b 1.05 (0.83–1.32) NS 2.14 (1.59–2.90) < 0.001
Age > 70b 0.91 (0.73–1.13) NS 3.71 (2.79–4.93) < 0.001
MCCI (2, 3)c 0.87 (0.71–1.08) NS 1.75 (1.36–2.24) < 0.001
MCCI (>  3)c 1.14 (0.94–1.40) NS 2.76 (2.18–3.51) < 0.001
Post BSI AVFa 0.94 (0.46–1.93) NS 0.83 (0.50–1.39) NS
TCa 1.68 (0.77–3.70) NS 1.30 (0.72–2.34) NS
NTCa 2.29 (1.09–4.82) 0.030 3.20 (1.86–5.50) < 0.001
Sex 1.14 (0.81–1.60) NS 1.07 (0.83–1.38) NS
Age 50–59b 1.47 (0.85–2.56) NS 1.53 (0.82–2.86) NS
Age 60–69b 1.25 (0.75–2.10) NS 2.56 (1.50–4.37) < 0.001
Age > 70c 1.35 (0.81–2.23) NS 5.41 (3.26–9.00) < 0.001
MCCI (2, 3)c 1.70 (0.94–3.07) 0.081 1.96 (1.20–3.20) 0.008
MCCI (>  3)c 2.99 (1.72–5.19) < 0.001 2.99 (1.88–4.74) < 0.001
Gram + 0.89 (0.62–1.27) NS 0.77 (0.59–0.99) 0.044
  1. HD hemodialysis, AVF arteriovenous fistula, TC tunneled catheter, NTC non-tunneled catheter, MCCI modified Charlson comorbidity index, NS not significant, HR hazard ratio, CI confidence interval
  2. a Analyzed as a four-leveled variable with peritoneal dialysis as reference
  3. b Analyzed as a four-leveled variable with ‘age < 50 years’ as reference
  4. c Analyzed as a three-leveled variable with ‘MCCI = 1’ as reference