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Table 2 Main viro-immunological parameters of SSP and of VP according to the detection or not of HHV-8 shedding at T0 regardless of the presence or absence of EBV and/or CMV salivary shedding. Data are expressed as median and interquartile range (IQR). In bold significant P values

From: Cytomegalovirus, Epstein-Barr virus and human herpesvirus 8 salivary shedding in HIV positive men who have sex with men with controlled and uncontrolled plasma HIV viremia: a 24-month longitudinal study

  SSP with HHV-8 shedding (n = 14) VP with HHV-8 shedding (n = 15) p SSP with no HHV-8 shedding (n = 26) VP with no HHV-8 shedding (n = 18) p
CD4 + cell count/mm3 590 (520–690) 600(447–677) 0.69 630(400–850) 535(310–620) 0.17
CD4+ cell percentage 26(24–36) 23 (21–30) 0.11 32 (22–36) 22.5 (15–28) 0.01
CD8+ cell count/mm 993 (522–1248) 1106 (1014–1403) 0.27 821 (619–1153) 1106 (1010–1524) 0.009
CD8 + cell percentage 44 (30–51) 50 (47–53) 0.09 43 (35–52) 53.5 (48–60) P < 0.001
CD4+ cell count at nadir (cells/mm3) 235 (140–340) 440 (340–567) 0.001 310(124–460) 470 (300–530) 0.09
  1. T0: time of the first saliva sampling, after 24 months of plasma HIV RNA control analysis
  2. SSPs HIV successfully suppressed patients, VPs HIV viremic patients