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Table 4 The difference of drug susceptibility between Beijing genotype family and non-Beijing genotype family when considered first-line drug resistance (n = 1189)

From: Characterization of Mycobacterium tuberculosis strains in Beijing, China: drug susceptibility phenotypes and Beijing genotype family transmission

Characteristic Category Total New cases Retreated cases
Number of reported cases Beijing family (%) Non-Beijing family (%) OR (95% CI) p value Number of reported cases Beijing family (%) Non-Beijing family (%) OR (95% CI) p value Number of reported cases Beijing family (%) Non-Beijing family (%) OR (95% CI) p value
All   1189 990 199    1065 885 180    124 105 19   
DST profile Pansusceptible 849 710(71.7) 139(69.9) 1.027(0.930–1.134) 0.325 800 667(75.4) 133(73.9) 1.020(0.928–1.121) 0.348 49 43(41) 6(31.6) 1.297(0.644–2.613) 0.221
  INH 205 161(16.3) 44(22.1) 0.736(0.547–0.989) 0.032 141 110(12.4) 31(17.2) 0.722(0.501–1.040) 0.042 64 51(48.6) 7(36.9) 1.318(0.709–2.453) 0.173
  RIF 119 99(10) 20(10.1) 0.995(0.631–1.569) 0.534 64 53(6) 11(6.1) 0.980(0.522–1.839) 0.475 55 46(43.8) 9(47.4) 0.925(0.549–1.557) 0.337
  SM 226 185(18.7) 41(20.6) 0.907(0.670–1.227) 0.295 176 143(16.2) 33(18.3) 0.881(0.625–1.242) 0.237 50 42(40) 8(42.1) 0.950(0.534–1.692) 0.431
  EMB 161 129(13) 32(16.1) 0.810(0.568–1.157) 0.151 117 92(10.4) 25(13.9) 0.748(0.496–1.130) 0.086 44 37(35.2) 7(36.9) 0.956(0.503–1.820) 0.447
  MDR 107 88(8.9) 19(9.6) 0.931(0.581–1.492) 0.427 58 48(5.4) 10(5.6) 0.976(0.503–1.893) 0.473 49 40(38.1) 9(47.4) 0.804(0.472–1.370) 0.224
  1. INH Isoniazid, LFP Rifampicin; SM Streptomycin; EMB Ethambutol; MDR multi-drug resistance
  2. p value indicates whether there is a significant difference between Beijing family and non-Beijing family (p < 0.05 represents a statistically significant difference)