Table 4 Details of specimens discrepant from the TP reference result in two or more assays
From: Laboratory evaluation of four HIV/syphilis rapid diagnostic tests
WHO N° | Origin | INSTI Multiplex HIV-1/HIV-2/Syphilis antibody test | DPP HIV/Syphilis Assay | SD Bioline HIV/Syphilis Duo | Multiplo rapid TP/HIV Antibody test | Reference Results TP | Reference result for HIV | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitros Syphilis TPA assay | TP particle agglutination (TTPA) | RPR | RecomLine Treponema IgM | Reference result for TP | |||||||||||||
Initial | Final | Initial | Final | Initial | Final | Initial | Final | S/CO | Result | Â | Result | Â | Â | Â | |||
Initial result not correct in all four RDTs | |||||||||||||||||
 WHO3–0008 | South America | FN | FN | FN | FN | FN | FN | FN | FN | 11,60 | R | 160 | R | N | NT | Positive | Negative |
 140,017 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 11,80 | R | 640 | R | N | NT | Positive | Negative |
 140,020 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 8,50 | R | 320 | R | N | NT | Positive | Negative |
 140,087 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 22,00 | R | 320 | R | N | NT | Positive | Negative |
 140,127 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 20,90 | R | 320 | R | N | NT | Positive | Negative |
 140,148 | Europe | FN | FN | FN | FN | FN | FN | FN | FN | 7,97 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,150 | Europe | FN | FN | FN | FN | FN | FN | FN | FN | 4,65 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,176 | Europe | FN | FN | FN | FN | FN | FN | FN | FN | 11,60 | R | 1280 | R | N | NT | Positive | HIV-1 positive |
 140,179 | United States | FN | FN | FN | FN | FN | FN | FN | FN | 5,83 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,180 | Europe | FN | FN | FN | FN | FN | FN | FN | FN | 5,79 | R | 320 | R | N | NT | Positive | HIV-1 positive |
 140,207 | Europe | FN | FN | FN | FN | FN | FN | FN | FN | 36,40 | R | 640 | R | N | NT | Positive | HIV-1 positive |
 140,215 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 13,20 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,231 | Asia | FN | FN | FN | FN | FN | FN | FN | FN | 5,97 | R | 80 | R | N | NT | Positive | HIV-1 positive |
 991,126 | Africa | FN | FN | FN | FN | FN | FN | FN | FN | 5,16 | R | 160 | R | N | NT | Positive | HIV-1 positive |
Initial result not correct in three RDTs and one indeterminate result | |||||||||||||||||
 140,016 | Africa | FN | FN | FN | FN | IND | OK | FN | FN | 19,50 | R | 640 | R | N | NT | Positive | Negative |
 140,037 | Africa | FN | FN | FN | FN | IND | OK | FN | FN | 44,40 | R | 640 | R | R | NT | Positive | Negative |
 140,107 | Africa | FN | FN | FN | FN | IND | IND | FN | FN | 24,90 | R | 640 | R | N | NT | Positive | Negative |
 140,109 | Africa | FN | FN | FN | FN | IND | IND | FN | FN | 18,30 | R | 320 | R | R | NT | Positive | Negative |
 140,209 | Europe | FN | FN | FN | OK | IND | FN | FN | FN | 29,10 | R | 320 | R | N | NT | Positive | HIV-1 positive |
Initial result not correct in two RDTs and two indeterminate results | |||||||||||||||||
 140,006 | Africa | FN | FN | IND | IND | IND | OK | FN | FN | 59,80 | R | 640 | R | N | NT | Positive | Negative |
 140,170 | Europe | FN | FN | IND | FN | IND | OK | FN | FN | 14,40 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,208 | Europe | FN | FN | IND | FN | IND | OK | FN | FN | 40,90 | R | 640 | R | N | NT | Positive | HIV-1 positive |
Initial result not correct in tree RDTs | |||||||||||||||||
 140,009 | Africa | FN | FN | FN | OK | OK | OK | FN | FN | 54,80 | R | 1280 | R | N | NT | Positive | Negative |
 140,149 | Europe | OK | OK | FN | FN | FN | FN | FN | FN | 42,60 | R | 320 | R | N | NT | Positive | HIV-1 positive |
 991,110 | Africa | FN | FN | FN | FN | FN | FN | OK | OK | 8,68 | R | 80 | R | N | NT | Positive | HIV-1 positive |
Initial result not correct in two RDTs and one indeterminate result | |||||||||||||||||
 140,085 | Africa | FN | FN | IND | FN | OK | OK | FN | FN | 7,90 | R | 160 | R | N | NT | Positive | Negative |
 140,091 | Africa | FN | FN | OK | OK | IND | IND | FN | IND | 31,50 | R | 640 | R | N | NT | Positive | Negative |
 140,146 | Europe | FN | FN | IND | IND | OK | OK | FN | FN | 19,30 | R | 80 | R | N | NT | Positive | HIV-1 positive |
 140,160 | Europe | OK | OK | IND | FN | FN | FN | FN | FN | 425,00 | R | 5120 | R | N | NT | Positive | HIV-1 positive |
 140,167 | Europe | FN | FN | OK | OK | IND | FN | FN | FN | 27,10 | R | 640 | R | N | NT | Positive | HIV-1 positive |
 140,192 | Europe | FN | FN | IND | OK | OK | OK | FN | FN | 15,00 | R | 320 | R | N | NT | Positive | HIV-1 positive |
Initial result not correct in two RDTs | |||||||||||||||||
 140,056 | Africa | FN | FN | OK | OK | OK | OK | FN | FN | 33,00 | R | 640 | R | N | NT | Positive | Negative |
 140,111 | Africa | FN | FN | OK | OK | OK | OK | FN | FN | 57,00 | R | 640 | R | N | NT | Positive | Negative |
 140,133 | Africa | FN | FN | OK | OK | OK | OK | FN | IND | 61,40 | R | 640 | R | N | NT | Positive | Negative |
 140,134 | Africa | FN | FN | OK | OK | OK | OK | FN | FN | 46,80 | R | 1280 | R | N | NT | Positive | Negative |
 140,140 | Europe | FN | OK | OK | OK | OK | OK | FN | FN | 35,40 | R | 320 | R | N | NT | Positive | HIV-1 positive |
 140,141 | Africa | FN | OK | OK | OK | OK | OK | FN | FN | 64,80 | R | 320 | R | N | NT | Positive | HIV-1 positive |
 140,152 | Europe | FN | FN | OK | OK | OK | OK | FN | FN | 18,20 | R | 160 | R | N | NT | Positive | HIV-1 positive |
 140,174 | Europe | FN | FN | OK | OK | OK | OK | IND | FN | 29,30 | R | 320 | R | R | NT | Positive | HIV-1 positive |
 140,219 | Europe | FN | FN | OK | OK | OK | OK | FN | FN | 41,50 | R | 640 | R | N | NT | Positive | HIV-1 positive |
 140,223 | Europe | FN | FN | OK | OK | OK | OK | FN | IND | 42,50 | R | 640 | R | N | NT | Positive | HIV-1 positive |
 140,230 | South America | FN | FN | OK | OK | OK | OK | FN | FN | 53,60 | R | 320 | R | N | NT | Positive | HIV-1 positive |
 WHO3–0586 | Africa | FR | FR | OK | OK | OK | OK | FR | FR | 0,02 | NR | – | NR | N | Negative | Negative | HIV-1 positive |