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Table 4 Details of specimens discrepant from the TP reference result in two or more assays

From: Laboratory evaluation of four HIV/syphilis rapid diagnostic tests

WHO N° Origin INSTI Multiplex HIV-1/HIV-2/Syphilis antibody test DPP HIV/Syphilis Assay SD Bioline HIV/Syphilis Duo Multiplo rapid TP/HIV Antibody test Reference Results TP Reference result for HIV
Vitros Syphilis TPA assay TP particle agglutination (TTPA) RPR RecomLine Treponema IgM Reference result for TP
Initial Final Initial Final Initial Final Initial Final S/CO Result   Result    
Initial result not correct in all four RDTs
 WHO3–0008 South America FN FN FN FN FN FN FN FN 11,60 R 160 R N NT Positive Negative
 140,017 Africa FN FN FN FN FN FN FN FN 11,80 R 640 R N NT Positive Negative
 140,020 Africa FN FN FN FN FN FN FN FN 8,50 R 320 R N NT Positive Negative
 140,087 Africa FN FN FN FN FN FN FN FN 22,00 R 320 R N NT Positive Negative
 140,127 Africa FN FN FN FN FN FN FN FN 20,90 R 320 R N NT Positive Negative
 140,148 Europe FN FN FN FN FN FN FN FN 7,97 R 160 R N NT Positive HIV-1 positive
 140,150 Europe FN FN FN FN FN FN FN FN 4,65 R 160 R N NT Positive HIV-1 positive
 140,176 Europe FN FN FN FN FN FN FN FN 11,60 R 1280 R N NT Positive HIV-1 positive
 140,179 United States FN FN FN FN FN FN FN FN 5,83 R 160 R N NT Positive HIV-1 positive
 140,180 Europe FN FN FN FN FN FN FN FN 5,79 R 320 R N NT Positive HIV-1 positive
 140,207 Europe FN FN FN FN FN FN FN FN 36,40 R 640 R N NT Positive HIV-1 positive
 140,215 Africa FN FN FN FN FN FN FN FN 13,20 R 160 R N NT Positive HIV-1 positive
 140,231 Asia FN FN FN FN FN FN FN FN 5,97 R 80 R N NT Positive HIV-1 positive
 991,126 Africa FN FN FN FN FN FN FN FN 5,16 R 160 R N NT Positive HIV-1 positive
Initial result not correct in three RDTs and one indeterminate result
 140,016 Africa FN FN FN FN IND OK FN FN 19,50 R 640 R N NT Positive Negative
 140,037 Africa FN FN FN FN IND OK FN FN 44,40 R 640 R R NT Positive Negative
 140,107 Africa FN FN FN FN IND IND FN FN 24,90 R 640 R N NT Positive Negative
 140,109 Africa FN FN FN FN IND IND FN FN 18,30 R 320 R R NT Positive Negative
 140,209 Europe FN FN FN OK IND FN FN FN 29,10 R 320 R N NT Positive HIV-1 positive
Initial result not correct in two RDTs and two indeterminate results
 140,006 Africa FN FN IND IND IND OK FN FN 59,80 R 640 R N NT Positive Negative
 140,170 Europe FN FN IND FN IND OK FN FN 14,40 R 160 R N NT Positive HIV-1 positive
 140,208 Europe FN FN IND FN IND OK FN FN 40,90 R 640 R N NT Positive HIV-1 positive
Initial result not correct in tree RDTs
 140,009 Africa FN FN FN OK OK OK FN FN 54,80 R 1280 R N NT Positive Negative
 140,149 Europe OK OK FN FN FN FN FN FN 42,60 R 320 R N NT Positive HIV-1 positive
 991,110 Africa FN FN FN FN FN FN OK OK 8,68 R 80 R N NT Positive HIV-1 positive
Initial result not correct in two RDTs and one indeterminate result
 140,085 Africa FN FN IND FN OK OK FN FN 7,90 R 160 R N NT Positive Negative
 140,091 Africa FN FN OK OK IND IND FN IND 31,50 R 640 R N NT Positive Negative
 140,146 Europe FN FN IND IND OK OK FN FN 19,30 R 80 R N NT Positive HIV-1 positive
 140,160 Europe OK OK IND FN FN FN FN FN 425,00 R 5120 R N NT Positive HIV-1 positive
 140,167 Europe FN FN OK OK IND FN FN FN 27,10 R 640 R N NT Positive HIV-1 positive
 140,192 Europe FN FN IND OK OK OK FN FN 15,00 R 320 R N NT Positive HIV-1 positive
Initial result not correct in two RDTs
 140,056 Africa FN FN OK OK OK OK FN FN 33,00 R 640 R N NT Positive Negative
 140,111 Africa FN FN OK OK OK OK FN FN 57,00 R 640 R N NT Positive Negative
 140,133 Africa FN FN OK OK OK OK FN IND 61,40 R 640 R N NT Positive Negative
 140,134 Africa FN FN OK OK OK OK FN FN 46,80 R 1280 R N NT Positive Negative
 140,140 Europe FN OK OK OK OK OK FN FN 35,40 R 320 R N NT Positive HIV-1 positive
 140,141 Africa FN OK OK OK OK OK FN FN 64,80 R 320 R N NT Positive HIV-1 positive
 140,152 Europe FN FN OK OK OK OK FN FN 18,20 R 160 R N NT Positive HIV-1 positive
 140,174 Europe FN FN OK OK OK OK IND FN 29,30 R 320 R R NT Positive HIV-1 positive
 140,219 Europe FN FN OK OK OK OK FN FN 41,50 R 640 R N NT Positive HIV-1 positive
 140,223 Europe FN FN OK OK OK OK FN IND 42,50 R 640 R N NT Positive HIV-1 positive
 140,230 South America FN FN OK OK OK OK FN FN 53,60 R 320 R N NT Positive HIV-1 positive
 WHO3–0586 Africa FR FR OK OK OK OK FR FR 0,02 NR NR N Negative Negative HIV-1 positive
  1. ITG specimens obtained through the ITM clinic; FR false reactive, FN false non-reactive, OK result is concordant with the reference result, IND indeterminate result, S/CO sample signal/cut-off, OD/CO optical density/cut-off, R reactive, NR non-reactive, NT not tested, N negative