Fig. 4

Forest plots showing the commonly reported adverse-events related to the antimalaria chemoprophylaxis in SCD patients. Results are shown for (a) hospitalization, (b) blood transfusion, (c) vaso-occlusive crisis and (d) mortality with placebo as a reference. The square area denotes the contribution of the drug to the meta-analysis. Horizontal line denotes the odds ratio together with the confidence intervals. The diamond represents the combined odds ratio with its confidence interval. Odd Ratios lower than 1 favour interventions and 95% CI values (Lower limit and Upper limit) comprised between 0 and 1 is associated with a significant difference