Table 3 Capture–recapture analysis of all hepatitis A cases and of subgroups, Catalonia 2011 to 2015
From: Hepatitis A surveillance: sensitivity of two information sources
No. records in SDR | No. records in MRS | Matched records | Calculated unreported cases | Estimated total no. of cases (95% CI) | SDR Sensitivity (%) (95% CI) | MRS Sensitivity (%) (95% CI) | Difference in sensitivity of the two sources | p-value | |
|---|---|---|---|---|---|---|---|---|---|
All cases | 547 | 216 | 105 | 463 | 1121 (985–1258) | 48.8 (43.5–55.6) | 19.3 (17.2–21.9) | 29.5% | < 0.001 |
Age at notification, years | |||||||||
< 15 years | 302 | 99 | 76 | 68 | 393 (357–430) | 76.6 (72.7–81.0) | 25.2 (20.9–29.5) | 51.4% | < 0.001 |
> = 15 years | 245 | 116 | 29 | 627 | 959 (687–1232) | 25.5 (22.8–28.3) | 12.1 (10.0–14.2) | 13.4% | |
Sex | 0.667 | ||||||||
Male | 308 | 126 | 58 | 288 | 664 (554–775) | 46.4 (39.8–55.7) | 19.0 (16.3–22.8) | 27.4% | |
Female | 239 | 90 | 47 | 172 | 454 (376–533) | 52.6 (44.9–63.6) | 19.8 (16.9–24.0) | 32.8% | |
Year of declaration | |||||||||
Year 2011 | 134 | 18 | 9 | 155 | 268 (168–369) | 50.0 (36.4–79.9) | 6.7 (4.9–10.7) | 43.3% | Ref |
Year 2012 | 127 | 50 | 34 | 44 | 187 (158–216) | 68.0 (58.8–80.6) | 26.8 (23.2–31.7) | 41.2% | < 0.001 |
Year 2013 | 107 | 31 | 21 | 41 | 158 (126–190) | 67.7 (56.3–85.5) | 19.6 (16.3–24.6) | 48.1% | 0.005 |
Year 2014 | 101 | 62 | 22 | 144 | 285 (207–364) | 35.5 (27.8–48.9) | 21.8 (17.1–30.1) | 13.7% | 0.015 |
Year 2015 | 74 | 55 | 19 | 104 | 214 (153–276) | 34.6 (26.8–48.5) | 25.7 (19.9–36.1) | 8.9% | 0.008 |
Size of municipality | 0.070 | ||||||||
< 10,000 people | 115 | 75 | 33 | 102 | 259 (205–312) | 44.5 (38.5–50.6) | 29.0 (23.5–34.6) | 15.5% | |
> =10,000 people | 430 | 127 | 72 | 270 | 755 (652–858) | 57.0 (53.5–60.5) | 16.8 (14.2–19.5) | 40.2% | |
Country of birth | < 0.001 | ||||||||
Spain | 186 | 88 | 50 | 101 | 325 (376–375) | 57.2 (49.6–67.4) | 27.1 (23.5–31.9) | 30.1% | |
Other countries | 92 | 78 | 45 | 34 | 159 (138–180) | 58.0 (51.2–66.8) | 49.1 (43.4–56.6) | 8.9% | |
Type of notification | < 0.001 | ||||||||
Electronic | 184 | 37 | 17 | 186 | 390 (269–511) | 47.2 (36.0–68.5) | 9.5 (7.3–13.8) | 37.8% | |
Paper | 363 | 179 | 88 | 281 | 735 (642–830) | 49.4 (43.8–56.6) | 24.4 (21.6–27.9) | 15.8% | |
Centre of notification | 0.704 | ||||||||
Primary health care centre | 184 | 65 | 29 | 186 | 406 (310–503) | 45.3 (36.6–59.5) | 16.0 (12.9–21.0) | 45.1% | |
Hospital | 182 | 151 | 76 | 103 | 360 (318–404) | 50.5 (45.2–57.3) | 41.9 (37.5–47.6) | 5.6% | |