| |
Severe dengue
|
No severe dengue
|
Univariate analysis
|
P value
|
Multivariate analysis
|
P value
|
|---|
|
N = 20
|
N = 408
|
Unadjusted OR or coefficient (95% CI)
|
Adjusted OR or coefficient (95% CI)
|
|---|
|
Age, years
|
36 (27–50)
|
35 (27–45)
|
1.0 (0.99–1.05)
|
0.21
|
0.98 (0.94–1.0)
|
0.41
|
|
Male sex
|
10 (50)
|
217 (53)
|
0.88 (0.36–2.2)
|
0.78
| | |
|
Low socioeconomic status
|
5 (25)
|
173 (42)
|
0.45 (0.16–1.3)
|
0.13
| | |
|
Black race
|
6 (30)
|
234 (57)
|
0.32 (0.12–0.85)
|
0.02
|
0.26 (0.09–0.77)
|
0.02
|
|
Private clinic
|
14 (70)
|
229 (56)
|
1.8 (0.69–4.8)
|
0.22
| | |
|
Malaria coinfection
|
0 (0)
|
15 (3.7)
| | | | |
|
Pregnancy
|
0 (0)
|
8 (2.0)
| | | | |
|
History of diabetes
|
3 (15)
|
3 (0.74)
|
24 (4.5–127)
|
< 0.001
|
43 (5.2–361)
|
< 0.001
|
|
Secondary dengue
|
3 (15)
|
554 (13.2)
|
1.2 (0.33–4.1)
|
0.82
|
1.5 (0.40–5.4)
|
0.56
|
|
Warning signs
|
9 (45)
|
120 (29)
|
2.0 (0.79–4.9)
|
0.14
| | |
|
Abdominal pain
|
4 (20)
|
62 (15)
|
1.4 (0.45–4.3)
|
0.56
| | |
|
Persistent vomiting
|
4 (20)
|
36 (8.8)
|
2.6 (0.82–8.1)
|
0.1
| | |
|
Clinical fluid accumulation
|
1 (5)
|
3 (0.74)
|
7.1 (0.71–71.5)
|
0.1
| | |
|
Mucosal bleed
|
5 (25)
|
33 (8)
|
3.8)1.3–11)
|
0.02
| | |
|
Laboratory parameters a
|
|
Hematocrit, %
|
43 (41–46)
|
42 (38–46)
|
1.0 (0.95–1.1)
|
0.69
| | |
|
Hematocrit > 45%
|
7 (35)
|
113 (28)
|
1.4 (0.55–3.61)
|
0.48
| | |
|
Platelets, ×109/L
|
146 (103–186)
|
150 (116–189)
|
1.0 (0.99–1.0)
|
0.71
| | |
|
Platelets < 100 × 109/L
|
4 (20)
|
66 (16)
|
1.3 (0.42–4.0)
|
0.65
| | |
|
Leukocytes, ×109/L
|
9 (45)
|
134 (33)
|
0.99 (0.87–1.1)
|
0.83
| | |
|
Leukocytes < 3.5 × 109/L
|
9 (45)
|
134 (33)
|
1.7 (0.68–4.13)
|
0.27
| | |
- aBlood count values missing in 18 patients
