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Table 3 Community-acquired pneumonia definition patterns of the 47 trials according to the characteristics of the trials

From: High heterogeneity in community-acquired pneumonia inclusion criteria: does this impact on the validity of the results of randomized controlled trials?

CAP definition pattern

Number of trials

Type of trial

Non-inferiority

Superiority

NS

1

Infiltrate on chest X-ray

3

1

2

and ≥ 1 respiratory symptom

    

and fever

    

and biological inflammatory sd

    

2

Infiltrate on chest X-ray

3

3

and ≥ 1 respiratory symptom

    

and fever

    

3

Infiltrate on chest X-ray

11

9

2

and ≥ 1 respiratory symptom

    

4

Infiltrate on chest X-ray

8

5

1

2

and ≥ 2 respiratory symptoms

    

5

Infiltrate on chest X-ray

19

4

2

13

and ≥ 1 criterion / >  2 criteria among

    

 -fever

    

 -respiratory symptom

    

 -biological inflammatory sd

    

6

Fever

1

1

and dyspnoea / polypnoea

    

and new cough

    

and purulent sputum

    

and abnormal pulmonary auscultation

    

7

Fever

1

1

and new sputum

    

and ≥ 2 criteria among

    

 -dyspnoea

    

 -polypnoea

    

 -chest pain

    

8

Infiltrate on chest X-ray

1

1

and ≥ 4 criteria among

    

 -fever

    

 -respiratory symptoms

    
  1. NS Type of study not specified, AB Antibiotic, sd Syndrome, CAP Community-acquired pneumonia