Evaluation of Senegal’s prevention of mother to child transmission of HIV (PMTCT) program data for HIV surveillance

Diouf, Ousmane; Gueye-Gaye, Astou; Sarr, Moussa; Mbengue, Abdou Salam; Murrill, Christopher S.; Dee, Jacob; Diaw, Papa Ousmane; Ngom-Faye, Ndeye Fatou; Diallo, Pape Amadou Niang; Suarez, Carlos; Gueye, Massaer; Mboup, Aminata; Toure-Kane, Coumba; Mboup, Souleymane

doi:10.1186/s12879-018-3504-z

Table 1 Individual-level agreement of PMTCT HIV testing results versus UAT surveillance

From: Evaluation of Senegal’s prevention of mother to child transmission of HIV (PMTCT) program data for HIV surveillance

Region	Site	N	Comparison between the results of HIV testing for PMTCT (R) and those of Sentinel Surveillance (S)				Positive Percent Agreement	Negative percent agreement	PMTCT HIV Prevalence (%)	UAT surveillance HIV Prevalence (%)
Region	Site	N	R-S+	R + S+	R + S-	R-S-	Positive Percent Agreement	Negative percent agreement	PMTCT HIV Prevalence (%)	UAT surveillance HIV Prevalence (%)
West	CS Mbao	174	1	4	0	169	80.0	100.0	2.9	2.3
	CS Roi Baudoin	196	0	2	0	194	100.0	100.0	1.0	1.0
	CS de Mbour	300	2	5	2	291	71.4	99.3	2.3	2.3
	CS khombole	272	0	2	0	270	100.0	100.0	0.7	0.7
	Centre de santé 10eme	238	1	7	1	229	87.5	99.6	3.4	3.4
	PMI Medina	300	0	3	0	297	100.0	100.0	1.0	1.0
	PS Nianing	138	0	2	0	136	100.0	100.0	1.4	1.4
	PS Nguekhokh	175	0	0	0	175	NA	100.0	0,0	0,0
	PS de Mboro	175	0	2	0	173	100.0	100.0	1.1	1.1
North	CS Dagana	166	0	1	1	164	100.0	99.4	0.6	1.2
	CS Linguere	99	0	1	0	98	100.0	100.0	1.0	1.0
	CS Matam	219	1	1	0	217	50.0	100.0	0.9	0.5
	CS Louga	272	0	0	0	272	NA	100.0	0,0	0,0
	CS Saint Louis	112	0	0	0	112	NA	100.0	0,0	0,0
	PS Bokidiawé	150	0	0	0	150	NA	100.0	0,0	0,0
	PS Ourossogui	186	0	2	0	184	100.0	100.0	1.1	1.1
	PS de Samyabal	159	0	1	0	158	100.0	100.0	0.6	0.6
Centre	CS Diourbel	297	1	5	0	291	83.3	100.0	2.0	1.7
	CS Fatick	164	0	2	0	162	100.0	100.0	1.2	1.2
	CS Kasnack	299	0	3	0	296	100.0	100.0	1.0	1.0
	CS Koungheul	279	0	2	0	277	100.0	100.0	0.7	0.7
	CS Ndoffane	175	0	3	0	172	100.0	100.0	1.7	1.7
	CS Sokone	293	2	2	0	289	50.0	100.0	1.4	0.7
	CS Touba	298	0	2	0	296	100.0	100.0	0.7	0.7
	CS kaffrine	184	0	3	0	181	100.0	100.0	1.6	1.6
	PS Dianké	119	0	0	0	119	NA	100.0	0,0	0,0
	PS Tataguine	175	0	0	0	175	NA	100.0	0,0	0,0
	PS de Ngoye	163	0	2	0	161	100.0	100.0	1.2	1.2
	SOS Kaolack	300	0	3	0	297	100.0	100.0	1.0	1.0
South	C.S Vélingara	81	0	1	3	77	100.0	96.3	1.2	4.9
	C.S de Goudomp	299	0	4	0	295	100.0	100.0	1.3	1.3
	C.S de Sédhiou	115	0	4	0	111	100.0	100.0	3.5	3.5
	CS C Senghor Ziguinchor	292	1	11	0	280	91.7	100.0	4.1	3.8
	CS Bignona	298	0	9	0	289	100.0	100.0	3.0	3.0
	CS Boumkiling	159	0	2	0	157	100.0	100.0	1.3	1.3
	CS Kolda	298	5	8	0	285	61.5	100.0	4.4	2.7
	CS Salémata	71	0	0	0	71	NA	100.0	0,0	0,0
	CS Saraya	33	0	0	0	33	NA	100.0	0,0	0,0
	CS Tambacounda	301	0	0	0	301	NA	100.0	0,0	0,0
	PS Missira	160	0	0	0	160	NA	100.0	0,0	0,0
	PS Diawara	175	0	0	2	173	NA	98.9	1,1	0,0
	PS Diaobé	150	4	2	0	144	33.3	100.0	4.0	1.3
	PS de Kabrousse	149	0	2	0	147	100.0	100.0	1.3	1.3
Overall		8658	18	103	9	8528	85.1 (77.2–90.7%),	99.9 (95%CI: 99.8–99.9)	Median = 1.1 (IQR: 1.0)	Median = 1.0 (IQR: 1.6)
Overall		8658	18	103	9	8528	85.1 (77.2–90.7%),	99.9 (95%CI: 99.8–99.9)	p-value = non-significant

1. Percentage of positive agreement = (R + S+/R + S+ and R-S+)
2. Percentage of negative agreement = (R-S-)/ (R-S- and R + S-)
With R−/R+ the results of HIV testing for PMTCT
And S-/S+ the results of HIV Sentinel Surveillance
a) The positive percentage agreement (PPA) was calculated as the proportion of pregnant women tested HIV-positive through ANC SS HIV testing (using a combined 4th generation ELISA) who were identified as HIV-positive through routine PMTCT testing (using a 2-rapid testing serial algorithm)
b) The negative percentage agreement (NPA) was calculated as the proportion of pregnant women tested HIV-negative through ANC SS HIV testing (using a combined 4th generation ELISA) who were identified as HIV-negative through routine PMTCT testing (using a 2-rapid testing serial algorithm)

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ISSN: 1471-2334

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