Table 1 Demography, clinical, and laboratory features both in hospital and reference laboratory
From: Case report: two confirmed cases of human Seoul virus infections in Indonesia
Patient | 1 | 2 |
|---|---|---|
Age (years) | 55 | 27 |
Gender | Female | Male |
City | Surabaya | Jakarta |
Dates of enrollment (days after fever onset) | 03/11/2015 [4] | 01/03/2016 [6] |
Duration of hospital stay (days) | 5 | 8 |
Symptoms and signs (at enrollment) | ||
 Fever | Yes | Yes |
 Anorexia | No | Yes |
 Headache/Dizziness | No | Yes |
 Decrease of consciousness | No | Yes |
 Lethargy | Yes | No |
 Abdominal/Epigastric pain | Yes | No |
 Diarrhea | No | No |
 Nausea | Yes | Yes |
 Vomiting | Yes | Yes |
 Retro orbital pain | Yes | No |
 Arthralgia | No | Yes |
 Jaundice | No | Yes |
Laboratory results (normal value range) (at day 1 enrollment) | ||
 Hematocrit (40–50%) | 38.8 | 50.6 |
 White blood cells (3500–9000/μL) | 3850 | 5790 |
 Neutrophils (39.8–70.5%) | 73.2 | 79 |
 Lymphocyte (23.1–49.9%) | 8.4 | 16 |
 Platelets (150–450 × 103/μL) | 50,000 | 24,700 |
 AST (<  41 IU/L) | 216 | 3900 |
 ALT (<  38 IU/L) | 116 | 891 |
 Blood Urea Nitrogen (BUN) (10–23 mg/dL) | 10 | 20.3 |
 Creatinine serum (0.5–1.2 mg/dL) | 0.57 | 1.16 |
 C-Reactive protein (< 5 mg/dL) | ND | 41.1 |
 Procalcitonin (< 0.5 ng/dL) | ND | 5.98 |
Diagnostic work-up for other pathogens at reference laboratory PCR results at day 1 enrollment sample | ||
 Dengue | Negative | Negative |
 Chikungunya | Negative | Negative |
 Zika | ND | Negative |
 Hantavirus | Positive | Positive |
 Seoul virus | Positive | Positive |
Serological results (day 1 enrollment-convalescent (convalescent samples were taken 58 and 28Â days after enrollment respectively for patient 1 and 2) | ||
 Dengue IgM | Negative − Negative | Negative – Negative |
 Dengue IgG | Positive − Positive | Negative − Negative |
 Chikungunya IgG | ND − Negative | ND − Negative |
 Salmonella IgM | Negative − Negative | Negative − Negative |
 Salmonella IgG | Negative − Negative | Negative − Negative |
 Leptospira IgM | Negative − Negative | Negative − Negative |
 Leptospira IgG | Negative − Negative | Negative − Negative |
 Hantavirus IgM | 1:800–1:400 | 1:200–1:3200 |
 Hantavirus IgG | 1:800–1:6400 | 1:400–1:12800 |
 Murine typhus IgG | ND − Negative | ND − Negative |
 Scrub typhus (IgG) | ND − Negative | ND − Negative |
 HIV antibody | Negative − Negative | Negative − Negative |