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Table 3 The iga protease gene variants among respiratory tract isolates with different properties

From: Differential distribution of IgA-protease genotypes in mucosal and invasive isolates of Haemophilus influenzae in Sweden

iga genotype

igaA1 alone

igaA2

igaB gene present

p-value

Age (continuous, year), mean (median)

29.4 (21)

18.1 (4)

33.5 (40)

< 0.001

Age category (n = 175, 2 missing)

   

0.042

  > 70 years, n (% within genotype)

5 (8%)

5 (6%)

 

 50–70 years, n (% within genotype)

14 (22%)

7 (13%)

20 (25%)

 

 20–50 years, n (% within genotype)

15 (24%)

14 (25%)

27 (34%)

 

 6–20 years, n (% within genotype)

5 (8%)

3 (5%)

6 (8%)

 

  < 6 years, n (% within genotype)

24 (38%)

31 (56%)

21 (27%)

 

Gender, % female

56%

53%

62%

0.684

Primary care referrals, %

71%

65%

64%

0.966

Clinical diagnosis (n = 175, 2 missing)

   

0.172

 AOM, n (% within genotype)

11 (17%)

13 (24%)

13 (16%)

 

 Sinusitis, n (% within genotype)

6 (10%)

6 (11%)

10 (13%)

 

 Upper respiratory tract infection, n (% within genotype)

26 (41%)

16 (29%)

24 (30%)

 

 Lower respiratory tract infection, n (% within genotype)

11 (17%)

3 (5%)

16 (20%)

 

 Unclear from referral, n (% within genotype)

9 (14%)

17 (31%)

16 (20%)

 
  1. The Kruskal-Wallis test for continuous variables and the chi-2 test for categorical variables were used. Significant p-values are indicated in bold