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Table 3 High dose fluconazole related adverse events in 44 cryptococcal meningitis patients

From: High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis

Adverse eventsa No. (%) of patients (N = 44)
Liver dysfunction
 GGT 10 (22.7)
 ALT 5 (11.4)
 AST 4 (9.1)
 ALP 1 (2.3)
Hematocytopenia
 Anemia 1 (2.3)
 Neutropenia 1 (2.3)
 Thrombocytopenia 1 (2.3)
Hypokalemia 3 (6.8)
Nausea and vomitting 5 (11.4)
Constipation 3 (6.8)
Dry mouth 2 (4.5)
Dry eyes 1 (2.3)
Skin lesion 2 (4.5)
Numbness of upper limb 1 (2.3)
Thrombosis of lower limb 1 (2.3)
  1. GGT gama-glutamyltransferase; ALT alanine aminotransferase; AST aspartate aminotransferase; ALP alkaline phosphatase
  2. aAll laboratory abnormalities were grade 1 or grade 2 only