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Table 1 Cases of Gemella berigeri from 1998 to 2018

From: Purpura fulminans with Lemierre’s syndrome caused by Gemella bergeri and Eikenella corrodens: a case report

Case

Age

Gender

Disease

Underlying disease

Antibiotics

Reson for changing antibiotics

Blood culture

How to diagnose

Operation

Outcome

Reference

1

42

Male

I ▪ E

Mitral valve prolapse, periodontitis

NA

NA

NA

16S rRNA gene sequence

Valve replacement

Admission

[5]

2

NA

NA

I・E

NA

NA

NA

NA

16S rRNA gene sequence

NA

Survived

[5]

3

NA

NA

I・E

NA

NA

NA

NA

16S rRNA gene sequence

NA

Survived

[5]

4a

NA

NA

NA

NA

NA

NA

NA

16S rRNA gene sequence

NA

Survived

[5]

5a

NA

NA

NA

NA

NA

NA

NA

16S rRNA gene sequence

NA

Survived

[5]

6a

NA

NA

NA

NA

NA

NA

NA

16S rRNA gene sequence

NA

Survived

[5]

7

32

Male

I・E

Bicuspid aortic valve

Ampicillin, gentamicin, refampicin

No

Gram-positive cocci

16S rRNA gene sequence

Ring abscess curettage, valve replacement

Survived

[6]

8

15

Male

I・E

Tetralogy of Fallot, pulmonary atresia

Vancomycin, gentamicin →ceftriaxone, refampicin

Side effect

Gram-positive cocci

16S rRNA gene sequence

No

Survived

[7]

9

24

Male

I・E

Rheumatic heart disease

Ceftriaxone, gentamicin

No

Gram-positive cocci

Phenotypic method

Decompressive craniotomy

Death

[8]

10

50

Male

I・E

Bicuspid aortic valve

Amoxicilline-clavulanate, amikacin →ceftriaxon, gentamicin

Antibiogram results

Gemella bergeri

NA

No

Survived

[9]

11

37

Male

I・E

Tricuspid valve cleft

NA

NA

Negative

Real-time PCR

Valve repair with vegetectomy

Survived

[10]

12

63

Male

I・E

Extensive dental procedure

Vancomycin, piperacillin-tazobactam, levofloxacin

No

Gram-positive cocci

Phenotypic method

No

Death

[4]

13

23

Male

I・E

Bicuspid aortic valve

Ceftriaxone, vancomycin →ampicillin, gentamicin

Antibiogram results

Gemella bergeri

NA

Mitral valve repair with vegetectomy, aortic valve replacement

Survived

[11]

  1. I・E Infective endocarditis, NA Not applicable, PCR Polymerase chain reaction, RNA Ribonucleic acid; aThese cases do not mention a clinical diagnosis and further clinical data