Prevalence and antibiotic susceptibility pattern of CTX-M type extended-spectrum β-lactamases among clinical isolates of gram-negative bacilli in Jimma, Ethiopia

Table 3 In vitro antimicrobial resistance pattern of CTX-M-positive Gram-negative isolates

Species	CTX-M positive isolate % resistance
Species	PI	PIT	CTX	CAZ	CPM	AT	IMP	MRP	AK	HLG	TOB	CIP	MOX	FO	TGC	CL	COT
E. coli (n = 13)	100	30.8	92.3	92.3	92.3	92.3	0	0	7.7	76.9	76.9	92.3	84.6	7.7	0	7.7	84.6
K. pneumoniae (n = 30)	100	60	100	96.7	96.7	96.7	0	0	0	90	96.7	66.7	80	0	0	0	93.3
E. cloacae (n = 9)	100	0	100	100	100	100	0	0	0	88.9	88.9	22.2	77.8	0	0	0	100
M. morganii (n = 3)	100	0	100	100	100	100	0	0	0	100	100	66.7	100	100	IR	IR	100
P. mirablis (n = 4)	100	0	100	100	100	100	0	0	0	100	100	25	25	50	IR	IR	75
P. stuartii (n = 2)	100	0	100	100	100	100	0	0	0	IR	IR	50	50	50	IR	IR	100
K. oxytoca (n = 2)	100	50	100	100	100	100	0	0	0	100	100	0	50	0	0	0	100
E. hermanii (n = 1)	R	R	R	R	R	R	S	S	S	R	R	R	R	S	S	S	R
Total Enterobacteriaceae (n = 64)	100	35.9	98.4	96.9	96.9	96.9	0	0	1.6	89.1	92.2	59.4	75	10.9	14.1	15.6	92.2
P. aeruginosa (n = 3)	66.7	66.7	IR	33.3	66.7	66.7	0	0	33.3	66.7	66.7	100	100	100	IR	0	IR
A. faecalis (n = 1)	R	S	IE	IE	IE	R	S	S	S	S	S	IE	S	IE	IE	IE	IE
Total GNB (n = 68)	98.5	36.8	97.1	92.6	94.1	95.6	0	0	2.9	88.2	91.2	60.3	76.5	14.7	17.6	14.7	91.2

Key: PI piperacillin, PIT piperacillin/tazobactam, CTX cefotaxime, CAZ ceftazidime, CPM cefepime, AT aztreonam, IMP imipenem, MRP meropenem, AK amikacin, HLG gentamicin, TOB tobramycin, CIP ciprofloxacin, MOX moxifloxacin, FO fosfomycine, TGC tigecycline, CL colistin, COT trimethoprim/sulfamethoxazole
n number of isolates, S sensitive, R resistant, IR intrinsic resistance, IE insufficient evidence

ISSN: 1471-2334