Fig. 4

SimPlot analysis of the complete genomic sequences of GII.4 Sydney 2012. SimPlot was constructed using a Simplot software version 3.5 with a slide window width of 200 bp and a step size of 20 bp. At each position of the window, the query sequence was compared to other Sydney 2012 variants sequenced in this study. The X-axis indicates the nucleotide positions in the multiple alignments of the NoV sequences; and the Y-axis indicates nucleotide difference (%) between the query sequence (BMH15–58) and other sequenced Sydney 2012 strains