Table 1 Patient Baseline Characteristics
From: Appropriate duration of post-surgical intravenous antibiotic therapy for pyogenic spondylodiscitis
Variable | All patients (n = 102) |
|---|---|
Age, year, mean (range) | 61 (18–87) |
Male sex | 65 (63.7%) |
Underlying illness | |
Alcoholism | 6 (5.9%) |
Diabetes mellitus | 33 (32.4%) |
Liver cirrhosis | 16 (15.7%) |
End-stage renal disease | 19 (18.6%) |
Intravenous drug abuser | 2 (2%) |
Malignancy | 8 (7.8%) |
Clinical data | |
Time to surgery, d, mean (range) | 41.77 (2–180) |
Back pain | 95 (93.1%) |
Fever | 34 (33.3%) |
Neurologic deficit | 23 (22.5%) |
Concurrent metastatic infection | 32(31.4%) |
Laboratory data (UNL) | |
Abnormal WBC (11,500 cells/mL) | 36 (35.3%) |
Abnormal ESR (30 mm/h) | 102 (100%) |
Abnormal CRP (5 mg/L) | 102 (100%) |
Positive blood culture | 32/85 (37.6%) |
Positive tissue culture | 77 (75.5%) |
MRSA infection | 25(24.5%) |
MSSA infection | 16 (15.7%) |
Radiographic data | |
Cervical spine infection | 3 (2.9%) |
Thoracic spine infection | 18 (17.6%) |
Lumbosacral spine infection | 81 (79.4%) |
More than 2 levels | 20 (19.6%) |
Epidural abscess | 38 (37.3%) |
Paraspinal abscess | 22 (21.6%) |
Radiographic finding | |
Anterior surgery | 29 (28.4%) |
Posterior surgery | 42 (41.2%) |
A + P surgery | 31 (30.4%) |
Instrumentation | 48 (47.1%) |
Post-op IV antibiotics ≤3 weeks | 41 (40.2%) |
Duration of pre-op IV antibiotics, d, mean (range) | 9.7 (0–60) |
Recurrence | 26 (25.5%) |