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Table 1 Patient Baseline Characteristics

From: Appropriate duration of post-surgical intravenous antibiotic therapy for pyogenic spondylodiscitis

Variable All patients (n = 102)
Age, year, mean (range) 61 (18–87)
Male sex 65 (63.7%)
Underlying illness
 Alcoholism 6 (5.9%)
 Diabetes mellitus 33 (32.4%)
 Liver cirrhosis 16 (15.7%)
 End-stage renal disease 19 (18.6%)
 Intravenous drug abuser 2 (2%)
 Malignancy 8 (7.8%)
Clinical data
 Time to surgery, d, mean (range) 41.77 (2–180)
 Back pain 95 (93.1%)
 Fever 34 (33.3%)
 Neurologic deficit 23 (22.5%)
 Concurrent metastatic infection 32(31.4%)
Laboratory data (UNL)
 Abnormal WBC (11,500 cells/mL) 36 (35.3%)
 Abnormal ESR (30 mm/h) 102 (100%)
 Abnormal CRP (5 mg/L) 102 (100%)
 Positive blood culture 32/85 (37.6%)
 Positive tissue culture 77 (75.5%)
 MRSA infection 25(24.5%)
 MSSA infection 16 (15.7%)
Radiographic data
 Cervical spine infection 3 (2.9%)
 Thoracic spine infection 18 (17.6%)
 Lumbosacral spine infection 81 (79.4%)
 More than 2 levels 20 (19.6%)
 Epidural abscess 38 (37.3%)
 Paraspinal abscess 22 (21.6%)
Radiographic finding
 Anterior surgery 29 (28.4%)
 Posterior surgery 42 (41.2%)
 A + P surgery 31 (30.4%)
 Instrumentation 48 (47.1%)
 Post-op IV antibiotics ≤3 weeks 41 (40.2%)
 Duration of pre-op IV antibiotics, d, mean (range) 9.7 (0–60)
Recurrence 26 (25.5%)
  1. Abbreviations: UNL upper normal limit, WBC white blood cells, ESR erythrocyte sedimentation rate, CRP C-reactive protein, MSSA methicillin-susceptible Staphylococcus aureus, MRSA methicillin-resistant Staphylococcus aureus