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Table 5 Differences in M. tuberculosis characteristics between the Beijing and non-Beijing families

From: Role of MIRU-VNTR and spoligotyping in assessing the genetic diversity of Mycobacterium tuberculosis in Henan Province, China

Drug susceptibility testing

total (n = 668)

Beijing family isolates(n = 558)

Non-Beijing family isolates (n = 110)

OR

95% CI

p-value

Pan sensitive

466

394

72

1.09

0.69–1.75

0.700

Any resistance to

 Isoniazid

99

85

14

1.23

0.67–2.26

0.487

 Rifampin

63

54

9

1.20

0.57–2.51

0.623

 Ethambutol

42

38

4

1.56

0.54–4.50

0.415

 Streptomycin

129

108

21

1.01

0.65–1.71

0.946

 Kanamycin

28

20

8

2.11

0.90–4.92

0.078

 ofloxacin

58

44

14

1.79

0.94–3.41

0.072

 All four first-line drugs resistance

30

29

1

5.97

1.05–44.33

0.045

 MDR-TB

50

47

3

3.28

1.01–10.37

0.038

 Pre-XDR-TB

17

16

1

3.21

0.42–24.51

0.332

 XDR-TB

11

10

1

1.99

0.25–15.69

1.001

  1. OR odds ratio, CI confidence interval
  2. MDR-TB: multi-drug resistance TB, resistant to at least isoniazid and rifampicin
  3. XDR-TB: extensively drug-resistant tuberculosis, MDR-TB plus resistance to ofloxacin and kanamycin
  4. Pre-XDR-TB: MDR-TB plus resistance to either ofloxacin or kanamycin
  5. First-line drugs resistance: resistant to isoniazid, rifampin, ethambutol and streptomycin
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BMC Infectious Diseases

ISSN: 1471-2334

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