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Table 6 Distribution of antimicrobial resistance by serotype. Only serotypes represented by more than 10 isolates are reported. Correlation between frequency of serotypes in study population and in MDR fraction is given in the last column

From: Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries

serotypes

N (%)

Ceftazidime (%)

Clarithromycin (%)

Clindamycin (%)

Penicillin (%)

Tetracyclin (%)

Trimethropim/ sulfamethoxazole (%)

MDR Fraction N (%)

p value

11A

60 (6.4)

8.3

6.7

3.3

5.0

0.0

10.0

5 (8,3)

0.090

23A

58 (6.2)

0.0

19.0

19.0

1.7

19

24.1

2 (3,4)

0.007*

19A

52 (5.5)

67.3

53.8

50

67.3

55.8

30.8

32 (61,5)

<  0.001*

3

50 (5.3)

0.0

0.0

0.0

0.0

0.0

2.0

0 (0,0)

0.001*

6C/D

44 (4.7)

6.8

29.5

27.3

27.3

25.0

0.0

11 (25,0)

0.001*

23B

39 (4.2)

12.8

0.0

0.0

30.8

0.0

28.2

11 (28,2)

0.093

19F

37 (3.9)

32.4

56.8

48.6

37.8

54.1

18.9

14 (37,8)

0.001*

23F

37 (3.9)

13.5

16.2

10.8

16.2

10.8

16.2

6 (16,2)

0.934

15B/C

35 (3.7)

2.9

8.6

0.0

22.9

11.4

31.4

3 (8,6)

0.255

35B

34 (3.6)

38.2

8.8

5.9

38.2

2.9

5.9

3 (8,8)

0.283

35F

33 (3.5)

6.1

3.0

3.0

0.0

0.0

0.0

1 (3,0)

0.050

22F

32 (3.4)

0.0

0.0

0.0

0.0

0.0

0.0

0 (0,0)

0.017*

6A

28 (3.0)

39.3

39.3

10.7

39.3

10.7

25.0

10 (35,7)

0.015*

10A

28 (3.0)

7.1

10.7

7.1

7.1

10.7

10.7

2 (7,1)

0.243

6B

25 (2.7)

24.0

32.0

28.0

20.0

28.0

24.0

8 (32,0)

0.081

15A

24 (2.6)

58.3

62.5

62.5

62.5

50

8.3

15 (62,5)

< 0.001*

17F

23 (2.5)

8.7

4.3

4.3

8.7

4.3

0.0

1 (4,3)

0.172

24F

21 (2.2)

28.6

28.6

28.6

28.6

28.6

19.0

6 (28,6)

0.260

18C

20 (2.1)

0.0

0.0

0.0

0.0

0.0

10.0

0 (0,0)

0.079

16F

19 (2.0)

0.0

15.8

15.8

0.0

15.8

42.1

1 (5,3)

0.282

37

17 (1.8)

0.0

0.0

0.0

0.0

0.0

5.9

0 (0,0)

0.117

7F

17 (1.8)

0.0

0.0

0.0

0.0

0.0

0.0

0 (0,0)

0.117

9 N

17 (1.8)

0.0

0.0

0.0

0.0

0.0

0.0

0 (0,0)

0.117

14

16 (1.7)

81.3

31.3

25.0

81.3

18.8

43.8

8 (50,0)

0.001*

33F

15 (1.6)

0.0

33.3

33.3

0.0

26.7

6.7

1 (6,7)

0.462

21

13 (1.4)

0.0

0.0

0.0

7.7

0.0

0.0

0 (0,0)

0.201

31

13 (1.4)

0.0

0.0

0.0

0.0

0.0

0.0

0 (0,0)

0.201

34

13 (1.4)

61.5

0.0

0.0

30.8

0.0

23.1

0 (0,0)

0.201

  1. *p < 0.05 is significant; MDR = Multidrug resistance; In bold: serotypes presenting the most MDR isolates; underlined: highly resistance