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Table 1 Primary amoebic meningoencephalitis cases reported in China and neighboring places

From: A case of Naegleria fowleri related primary amoebic meningoencephalitis in China diagnosed by next-generation sequencing

Age Gender Location Year First CSF after admission Amoebicidal Treatment Days from symptom onset to death Diagnosis
WBC (cells/μL) N % L % Glucose (mmol/L) Protein (g/L)
17 male Henanb 1978 50 5 95 2.95 1.52 NA 10 days Amoebic trophozoites were observed in the brain tissue after death.
21 male Beijingb 1990 300 70 30 3.4 0. 5 NA 7 days Amoebic trophozoites were found in the CSF after death.
23 male Hainanb 2001 22,000 85 NA 2.2 2 none 6 days Amoebic trophozoites were detected in the CSF before death.
38 male Hong Kong 1993 NA NA NA NA NA AmB, rifampicin survival Amoeba were observed in an abscess biopsy.
75 male Taiwan 2011 560 90.5 5 2.2 9.5 AmB 25 daysa Amoebic trophozoites were detected in the CSF.
42 male Shenzhen 2016 1170 83 12 1 3 AmB, fluconazole 15 days Next-generation sequencing
  1. CSF Cerebrospinal fluid, WBC White blood cells, N Neutrophils, L Lymphocytes, NA Not available
  2. aDays after the start of AmB treatment
  3. bSuspected cases documented in Chinese journals without an English citation version