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Table 4 Logistic models with logit links of association of dengue serotype and Age with immune response that lead to the evolution to a dengue fatal outcome

From: 30 years of dengue fatal cases in Brazil: a laboratorial-based investigation of 1047 cases

Variable Factor (vs.) Factor n (fatal/non-fatal) OR (95% CI) p value
Serotype Immune Responses    
‘n’ Primary Responses
DENV-1 Secondary 67 (5/62) 0.38 (0.14–0.96) 0.095
n = 57 (10/47)
DENV-2 Secondary 140 (46/94) 0.83 (0.49–1.41) 0.558
n = 62 (23/39)
DENV-3 Secondary 82 (19/63) 1.04 (0.60–1.79) 0.904
n = 138 (31/107)
DENV-4 Secondary 4 (04/00)
n = 8 (03/05)
Age Immune Responses    
(years old) ‘n’ Primary Responses
0–15 Secondary 46 (24/22) 3.93 (1.86–8.62) 0.003
n = 46 (10/36)
16–30 Secondary 63 (10/53) 0.6 (0.28–1.26) 0.267
n = 63 (15/48)
31–50 Secondary 100 (19/81) 0.95 (0.52–1.76) 0.89
n = 86 (17/69)
51–96 Secondary 51 (18/33) 1.83 (0.89–3.83) 0.172
n = 37 (18/19)
  1. To calculate each logistic GLM, Death/Alive outcome was coded as binary variable. Odd ratios (COR), 95% confidence intervals (95%CI) and p-values were calculated using one GLM for each studied variable separately. Values highlighted in bold presented: OR > 1, values of OR contained into the 95%CI range and p-values < 0.05