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Table 3 Cox regression hazards model for factors predicting all-cause mortality in 1264 newly diagnosed HIV infection

From: AIDS-related opportunistic illnesses and early initiation of HIV care remain critical in the contemporary HAART era: a retrospective cohort study in Taiwan

  Univariable analysis Multivariable analysisa
HR (95% CI) P AHR (95% CI) P
Age, per 10-year increase 2.00 (1.71–2.32) < 0.001 1.47 (1.21–1.77) < 0.001
Male sex 1.09 (0.15–7.86) 0.93 3.67 (0.48–28.34) 0.21
HIV transmission route
 Homosexual 1.00 (Reference)   1.00 (Reference)  
 Heterosexual 5.38 (3.03–9.55) < 0.001 2.61 (1.32–5.16) 0.006
 Bisexual 2.67 (1.03–6.90) 0.043 1.86 (0.71–4.88) 0.21
 IDU 2.64 (0.36–19.38) 0.34 1.98 (0.26–14.98) 0.51
 Unknown 11.14 (2.65–46.78) 0.001 5.87 (1.27–27.08) 0.011
Period
 Period 1 1.00 (Reference)    
 Period 2 1.32 (0.72–2.43) 0.37 1.48 (0.80–2.76) 0.21
 Period 3 0.71 (0.34–1.48) 0.35 0.92 (0.43–1.95) 0.82
Subgroup of CD4 cell count at presentation 17.59 (7.02–44.07) < 0.001   
 CD4 count ≥500 cells/μL 1.00 (Reference)   1.00 (Reference)  
 CD4 count 200–499 cells/μL 1.29 (0.15–11.03) 0.82 1.21 (0.14–10.42) 0.86
 CD4 count < 200 cells/μL 16.86 (2.33–122.04) 0.005 11.03 (1.51–80.64) 0.018
HBsAg seropositivity 3.30 (1.80–6.05) < 0.001 2.65 (1.42–4.94) 0.002
  1. Abbreviations: AHR adjusted hazard ratio, AOIs AIDS-defining opportunistic illnesses, CI confidence interval, HBsAg hepatitis B surface antigen, HCV hepatitis C virus, HR hazard ratio, IDU intravenous drug users
  2. aAll variables in the univariate analysis were selected for subsequent multivariate analysis