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Table 1 Risk factors associated with recent HEV infections in unadjusted and adjusted Cox regression analysis

From: Seroprevalence and risk factors of recent infection with hepatitis E virus during an acute outbreak in an urban setting in Chad, 2017

Factor Recent infections (N = 104) No infection (N = 429) Unadjusted PRs Adjusted PRs
PR (95%CI) p-value PR (95%CI) p-value
Age group [years]     0.08   0.04
0–4 33 (31.7%) 165 (38.5%) 0.84 (0.51–1.39)   0.88 (0.53–1.46)  
5–14 42 (40.4%) 125 (29.1%) 1.46 (0.89–2.39)   1.54 (0.94–2.51)  
≥15 29 (27.9%) 139 (32.4%) Reference Reference
Sex
 Female 55 (52.9%) 222 (51.8%) 1.02 (0.72–1.45) 0.89 1.07 (0.77–1.48) 0.68
Household composition
 At least one child < 5 years old 92 (88.5%) 357 (83.2%) 1.88 (1.06–3.3) 0.03 c
  > 6 persons 84 (80.8%) 328 (76.5%) 1.42 (0.89–2.26) 0.14 c
  ≥ 50% of the household with past HEV infection 53 (51.0%) 179 (41.7%) 1.37 (0.90–2.07) 0.14 c
Water, sanitation and hygiene
 Wide-mouthed containers owneda 92 (88.5%) 400 (93.5%) 0.62 (0.33–1.16) 0.13 c
 Shared sanitation facilityb 82 (80.4%) 287 (70.2%) 1.67 (0.88–3.16) 0.12 1.72 (1.08–2.73) 0.02
 No handwashing point next to the sanitation facilityb 67 (65.7%) 303 (74.1%) 0.72 (0.49–1.07) 0.11 c
 No systematic use of soap for handwashing 42 (40.4%) 107 (24.9%) 1.68 (1.14–2.48) 0.01 1.85 (1.30–2.63) < 0.01
 Animal sleeping inside the compound 35 (33.7%) 87 (20.3%) 1.65 (1.11–2.47) 0.02 1.69 (1.15–2.50) 0.01
  1. aIgM + =104 / IgM- = 428; b IgM + =102 / IgM- = 409; cNot kept in the final multivariate model