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Table 3 Impact of precise co-morbidities on 28-day mortality

From: Progression into sepsis: an individualized process varying by the interaction of comorbidities with the underlying infection

Co-morbidity

Odds ratio

95% confidence intervals

p-value

Patients with acute pyelonephritis

 Chronic heart failure

2.54

1.82–3.55

< 0.0001

 Chronic renal disease

1.71

1.13–2.60

0.011

 Non-metastatic solid tumor malignancy

2.13

1.44–3.17

< 0.0001

 Corticosteroid intake

2.05

1.09–3.84

0.024

 Stroke

2.97

2.12–4.17

< 0.0001

 Dementia

2.18

1.51–3.15

< 0.0001

Patients with community-acquired pneumonia

 Coronary heart disease

1.87

1.30–2.69

0.001

 Dementia

2.20

1.53–3.17

< 0.0001

Patients with intraabdominal infections

 Type 2 diabetes mellitus

1.84

1.16–2.93

0.010

 Chronic renal disease

2.67

1.12–6.35

0.026

 Non-metastatic solid tumor malignancy

3.03

1.79–5.13

< 0.0001

 Atrial fibrillation

2.23

1.11–4.48

0.024

 Dementia

3.69

1.87–7.25

< 0.0001

 Liver cirrhosis

4.59

1.20–17.51

0.025

Patients with primary bacteremia

 Dementia

3.87

1.65–9.12

0.002

  1. Only variables remaining significant after the final step of logistic forward conditional regression analysis are included