Table 1 Comparison of demographics of patients without sepsis and with sepsis in relation to the underlying infection

Number of patients

542

901

146

853

399

334

81

253

Male gender

(n, %)

145 (26.8)

361 (40.0)

< 0.0001

78

(53.4)

473 (55.4)

0.897

180

(45.2)

148

(45.1)

1.000

40

(49.4)

123

(48.6)

1.000

Age

(mean ± SD, years)

61.1 ± 22.0

74.8 ± 15.3

< 0.0001

61.4 ± 20.2

75.3 ± 14.9

< 0.0001

55.4 ± 24.3

74.7 ± 14.8

< 0.0001

63.3 ± 19.7

72.9 ± 14.5

< 0.0001

APACHE II score (mean ± SD)

9.2 ± 6.0

16.5 ± 7.4

< 0.0001

8.4 ± 4.8

18.4 ± 7.6

< 0.0001

7.5 ± 4.9

17.5 ± 8.9

< 0.0001

9.2 ± 4.6

19.8 ± 7.5

< 0.0001

SOFA score

(mean ± SD)

0.4 ± 0.5

5.9 ± 3.0

< 0.0001

0.7 ± 0.5

5.8 ± 3.2

< 0.0001

0.2 ± 0.5

5.3 ± 3.0

< 0.0001

0.5 ± 0.5

5.9 ± 3.4

< 0.0001

CCI

(mean ± SD)

3.0 ± 2.5

5.0 ± 2.6

< 0.0001

2.7 ± 2.3

4.8 ± 2.4

< 0.0001

2.3 ± 2.3

4.6 ± 2.4

< 0.0001

3.0 ± 2.0

4.5 ± 2.4

< 0.0001

28-day mortality

(n, %)

21

(3.9)

208 (23.1)

< 0.0001

7

(4.8)

323 (37.9)*

< 0.0001

17

(4.3)

109

(32.6)*

< 0.0001

4

(4.9)

98

(38.6)*

< 0.0001