Skip to main content

Table 5 Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

From: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Codon mutation in rpoB Codon mutation in katG Codon mutation in inhA No. of strains Frequency (%)
Ser531Leu Ser315Thr   42 34.7
Ser531Leu   C(−15) → T 32 26.4
Ser531Leu Ser315Thr C(−15) → T 2 1.7
Ser531LeuAsp516Tyr   C(−15) → T 2 1.7
Ser531LeuHis526Leu   C(−15) → T 1 0.8
His526Tyr Ser315Thr   13 10.7
His526Tyr   C(−15) → T 4 3.3
His526Leu Ser315Thr   2 1.7
His526Asp Ser315Thr   2 1.7
His526AspGln513Lys Ser315Thr   1 0.8
His526Arg Ser315Thr   1 0.8
Asp516Val Ser315Thr   2 1.7
Asp516Tyr Ser315Thr   2 1.7
Asp516Gly Ser315Thr   1 0.8
Asp516ValLeu511Pro   C(−15) → T 1 0.8
Asp516TyrLeu511Pro   C(−15) → T 1 0.8
Leu511Pro   C(−15) → T 2 1.7
Leu511Pro Ser315Thr   2 1.7
Leu511ProAsp516Gly Ser315Thr   2 1.7
Leu533Pro   C(−15) → T 2 1.7
Leu533Pro Ser315Thr   2 1.7
Leu533Pro Ser315Thr C(−15) → T 1 0.8
Gln513Lys Ser315Thr   1 0.8
Total    121