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Table 5 Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

From: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Codon mutation in rpoB

Codon mutation in katG

Codon mutation in inhA

No. of strains

Frequency (%)

Ser531Leu

Ser315Thr

 

42

34.7

Ser531Leu

 

C(−15) → T

32

26.4

Ser531Leu

Ser315Thr

C(−15) → T

2

1.7

Ser531LeuAsp516Tyr

 

C(−15) → T

2

1.7

Ser531LeuHis526Leu

 

C(−15) → T

1

0.8

His526Tyr

Ser315Thr

 

13

10.7

His526Tyr

 

C(−15) → T

4

3.3

His526Leu

Ser315Thr

 

2

1.7

His526Asp

Ser315Thr

 

2

1.7

His526AspGln513Lys

Ser315Thr

 

1

0.8

His526Arg

Ser315Thr

 

1

0.8

Asp516Val

Ser315Thr

 

2

1.7

Asp516Tyr

Ser315Thr

 

2

1.7

Asp516Gly

Ser315Thr

 

1

0.8

Asp516ValLeu511Pro

 

C(−15) → T

1

0.8

Asp516TyrLeu511Pro

 

C(−15) → T

1

0.8

Leu511Pro

 

C(−15) → T

2

1.7

Leu511Pro

Ser315Thr

 

2

1.7

Leu511ProAsp516Gly

Ser315Thr

 

2

1.7

Leu533Pro

 

C(−15) → T

2

1.7

Leu533Pro

Ser315Thr

 

2

1.7

Leu533Pro

Ser315Thr

C(−15) → T

1

0.8

Gln513Lys

Ser315Thr

 

1

0.8

Total

  

121

 
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BMC Infectious Diseases

ISSN: 1471-2334

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