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Table 3 Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

From: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Codon mutation Nucleic acid change No. of strains Frequency (%)
Ser531Leu TCG → TTG 30 52.6
His526Tyr CAC → TAC 7 12.3
His526Leu CAC → CTC 2 3.5
Leu511Pro CTG → CCG 5 8.8
Asp516Val GAC → GTC 2 3.5
Asp516Tyr GAC → TAC 3 5.3
Asp516Gly GAC → GGC 2 3.5
Gln513Lys CAA → AAA 1 1.8
Leu533Pro CTG → CCG 3 5.3
Ser531LeuLeu511Pro TCG → TTG CTG → CCG 1 1.8
Asp516TyrGln513LeuLeu511Pro GAC → TAC CAA → CCA CTG → CCG 1 1.8
Total   57