Table 3 Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples
Codon mutation | Nucleic acid change | No. of strains | Frequency (%) |
|---|---|---|---|
Ser531Leu | TCG → TTG | 30 | 52.6 |
His526Tyr | CAC → TAC | 7 | 12.3 |
His526Leu | CAC → CTC | 2 | 3.5 |
Leu511Pro | CTG → CCG | 5 | 8.8 |
Asp516Val | GAC → GTC | 2 | 3.5 |
Asp516Tyr | GAC → TAC | 3 | 5.3 |
Asp516Gly | GAC → GGC | 2 | 3.5 |
Gln513Lys | CAA → AAA | 1 | 1.8 |
Leu533Pro | CTG → CCG | 3 | 5.3 |
Ser531LeuLeu511Pro | TCG → TTG CTG → CCG | 1 | 1.8 |
Asp516TyrGln513LeuLeu511Pro | GAC → TAC CAA → CCA CTG → CCG | 1 | 1.8 |
Total | Â | 57 | Â |