Table 1 Review of cases report of tigecycline-induced acute pancreatitis --- demographic data and drug characteristics
Author | Country | Number of cases | Year of report | Age of patient | Gender | Indication of tigecycline | Culture of specimens | Duration of tigecycline (days) | Daily dose (mg) | Combination drug | Hitory of liver disease |
|---|---|---|---|---|---|---|---|---|---|---|---|
Glison M | France | 1 | 2008 | 35 | Male | Chronic osteitis complicated by pseudarthritis | Enterobacter cloacae with broad-spectrum betalactamase | 15 | 100 | Imipenem, amikacin | None |
Lipshitz J | Usa | 1 | 2009 | 64 | Female | Prosthetic joint infection | NA | 14 | 100 | Levothyroxine, | None |
Marshall RS | USA | 1 | 2009 | 55 | Female | Soft Tissue Infection | Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus hominis | 14 | NA | Pantoprazole, and hydromorphone. | None |
Hung WY | USA | 1 | 2009 | 69 | Female | Soft tissue infection/vascular graft infection | Coagulase-negative Staphylococcus, Staphylococcus epidermidis and diphtheroids, Clostridium difficile | 8 | 100 | Meropenem, vancomycin, clindamycin | None |
Prot-Labarthe S | France | 1 | 2010 | 9 | Male | Bacteriemia / arthritis | Enterobacter cloacae producing extended spectrum betalactamase | 56 | 100 | Colistin, amikacin and rifampin | None |
Otero RS | Mexico | 1 | 2010 | 27 | Female | Acute pneumonia | NA | 7 | 100 | Amikacin, oseltamivir | None |
Mascarello M | Italy | 1 | 2012 | NA | NA | Chronic osteomyelitis | methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii | 12 | 100 | Amikacin, propofol | None |
Hemphill MT | USA | 1st | 2015 | 22 | Male | Acute bronchitis | M. chelonae | 14 | NA | Tobramycin, meropenem, and vancomycin | None |
Hemphill MT | USA | 2nd | 2015 | 22 | Male | Acute bronchitis | M. chelonae | 3 | NA | Amikacin, clarithromycin | None |
Marot JC | Belgium | case 1 | 2012 | 64 | Male | Soft tissue infection | Staphylococcus aureus | 6 | 100 | None | None |
Marot JC | Belgium | case 2 | 2012 | 58 | Male | Soft tissue infection/osteomyelitis | Staphyloccus scleiferi methicillin-resistant and Staphylococcus lugdunensis methicillin-sensitive | 8 | 100 | Piperacillin-Tazobactam, Vancomycin | None |
Davido B | France | Case 1 | 2016 | 70 | Male | Pyelonephritis | ESBL Escherichia coli | 6 | 100 | None | None |
Davido B | France | Case 2 | 2016 | 50 | Female | Femoral osteomyelitis | EBSL E. coli, | 20 | 100 | Imipenem amikacin. | None |