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Table 1 Clinical and laboratory data of cirrhotic patients with BA and SBP

From: Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis

  Total (n = 600) BA (n = 192) SBP (n = 408) p
Sex (male) 465 (77.5%) 144 (75%) 321 (78.7%) 0.314
Age (yr) 53.9 ± 11.9 55.7 ± 12.1 53.1 ± 11.6 0.011
Presentation of symptoms 458 (76.3%) 118 (61.5%) 340 (83.3%) < 0.001
Nosocomial infection 287 (47.8%) 84 (43.8%) 203 (49.8%) 0.17
MELD score 19.7 ± 9.5 16.3 ± 7.9 21.4 ± 9.8 < 0.001
Days in hospital 13 (7–19) 13 (7–18) 13 (7–19) 0.732
Days between admission and onset of infection 2 (0–9) 2 (0–6) 2 (0–10) 0.03
Causes of cirrhosis     
Hepatitis B 370 (61.7%) 105 (54.7%) 265 (65%) 0.016
Hepatitis C 59 (9.8%) 24 (12.5%) 35 (8.6%) 0.132
Biliary 22 (3.7%) 7 (3.6%) 15 (3.7%) 0.985
Alcoholic 90 (15%) 37 (19.3%) 53 (13%) 0.044
Others 59 (9.8%) 19 (9.9%) 40 (9.8%) 0.972
Serum features     
ALT(U/L) 35.0 (21.0–64.0) 30.0 (20.0–48.0) 38.0 (21.0–71.8) 0.001
AST(U/L) 60.0 (37.0–105.8) 53.0 (33.0–86.0) 65.5 (39.0–111.8) 0.004
Prealbumin(mg/L) 47.2 ± 25.8 55.3 ± 23.9 43.4 ± 25.8 < 0.001
Prothrombin time(S) 18.1 (15.0–22.6) 54.5 (40.2–68.0) 41.8 (26.0–57.7) < 0.001
BUN(mmol/L) 8.0 (5.1–13.2) 6.4 (4.8–9.9) 8.9 (5.4–14.4) < 0.001
Serum PMN(cells/μL) 5.4 (3.0–8.6) 4.0 (2.4–6.4) 6.2 (3.6–9.8) < 0.001
Serum WBC(cells/μL) 6.9 (4.3–10.5) 5.4 (3.4–8.3) 7.7 (5.1–11.6) < 0.001
Creatinine (μmol/L) 97.5 (78.0–138.8) 90.0 (70.2–111.8) 105.0 (82.0–157.0) < 0.001
Total protein(g/L) 55.0 (49.0–61.0) 56.0 (51.0–63.0) 54.0 (48.0–60.0) 0.001
Total bilirubin (μmol/L) 82.4 (35.9–233.4) 51.5 (30.0–144.3) 107.9 (42.7–260.0) < 0.001
Ascitic features     
Ascitic PMN(cells/μL) 799.5 (53.1–5405.8) 22.9 (5.6–71.3) 3099.9 (720.2–7873.0) < 0.001
Ascitic WBC(cells/μL) 1241.0 (253.3–6565.0) 169.0 (90.3–310.8) 3850.5 (1119.3–9826.8) < 0.001
Hepatocellular carcinoma 175 (29.2%) 49 (25.5%) 126 (30.9%) 0.178
Hepatic encephalopathy 203 (33.8%) 58 (30.2%) 145 (35.5%) 0.198
Septic shock 108 (18%) 19 (9.9%) 89 (21.8%) < 0.001
Upper gastrointestinal bleeding 114 (19%) 34 (17.7%) 80 (19.6%) 0.580
Diabetes mellitus 101 (16.8%) 37 (19.3%) 64 (15.7%) 0.274
30-day mortality 131 (21.8%) 26 (13.5%) 105 (25.7%) 0.001
  1. Abbreviation: SBP spontaneous bacterial peritonitis, BA bacterascites, MELD Model for End-Stage Liver Disease, WBC white blood cell, PMN polymorphonuclear leukocytes, ALT alanine transarninase, AST aspartate aminotransferase, Bun blood urea nitrogen
  2. P:compared between BA and SBP. P-values < 0.05 are indicated in bold