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Table 3 Expression levels changes in RNAIII and agrA locus under exposure to oxacillin subMICs in the stationary growth phase clustered by methicillin resistance; Clonal Complex and agr type

From: Sub-inhibitory concentrations of oxacillin modify the expression of agr locus in Staphylococcus aureus clinical strains belonging to different clonal complexes

  RNAIII agrA
  subMIC OXA a vs. No subMIC OXA
Fold_Change
P b;c subMIC OXA vs. No subMIC OXA
Fold_Change
P
Methicillin resistance
 MRSA 2.26 POS 0.051 1.80 POS 0.163
 MSSA 1.75 POS 0.149 1.82 POS 0.003
Clonal complex
 CC45 1.74 POS 0.005 1.61 POS 0.000
 CC8 1.07 NEG 1.000 1.81 POS 0.022
 CC5 2.36 POS 0.108 3.61 POS 0.008
 CC15 3.48 POS 0.005 4.48 POS 0.001
 CC30 7.16 NEG 0.071 1.32 NEG 0.138
agr type
agrI 1.10 POS 0.804 1.62 POS 0.001
agrII 3.95 POS 0.001 3.98 POS 0.000
agrIII 7.16 NEG 0.071 1.32 NEG 0.138
  1. a OXA: Oxacillin
  2. b POS: fold change positive in the expression level under exposure to oxacillin subMIC. NEG: fold change negative in the expression level under exposure to oxacillin subMICs
  3. c Bold numbers indicate statistical significant results (P < 0.05)