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Table 3 Wisepill acceptability and experiences: themes identified from end-of-study questionnaire on device use and adherence monitoring

From: Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa

  N = 20* Percent**
Ease of using Wisepill
 Easy to use 19 95%
 Not easy to use 1 5%
 Prefer to use Wisepill for medications 19 95%
Medication(s) easiest to take with Wisepill
 ART 14 70%
 Levofloxacin 2 10%
 Bedaquiline 10 50%
Challenges of using Wisepill
 Difficulty opening the box 3 15%
 Required extra demonstration of how to use device 1 5%
 Worry that children will find/use the device 2 10%
 Fear of missing a dose 1 5%
 Worry about losing the box during travel 1 5%
 Disconcerted by the flashing light 1 5%
 Loss of confidentiality regarding disease status 0 0%
Benefits of using Wisepill
 Maintains confidentiality regarding disease status 6 30%
 Keeps medications safe 9 45%
 Keeps medications organized 3 15%
Perception of being monitored
 Motivates to take medications 9 45%
 Induces sense of being cared for 7 35%
Popularity of Wisepill device
 Fellow patients liked the device 11 55%
 Fellow patients disliked the loss of autonomy 1 5%
 Fellow patients fear repercussions of missing dose 1 5%
 Family would react positively to the device 18 90%
 Family would be curious about the device 1 5%
Recommendations
 Increase size of pillbox to accommodate more medications 10 50%
 Alarm/reminder to take medications 5 25%
 Device should have a color 1 5%
 Device should only be given to dedicated people 1 5%
  1. *20 of the 21 enrolled patients completed an end-of-study questionnaire
  2. **Patients expressed multiple views; percent reflects (number of patients)/(total number of patients) for each statement independently