From: Risk factors for hepatitis E virus seropositivity in Dutch blood donors
Overall (n = 1562) | Anti-HEV IgG-negative (n = 1074) | Anti-HEV IgG-positive (n = 488) | ||||
---|---|---|---|---|---|---|
N | % | N | % | N | % | |
Total | 1562 | 100 | 1074 | 68.8 | 488 | 31.2 |
A. Socio-demographic characteristics | ||||||
Gender | ||||||
Men | 1234 | 79.0 | 837 | 77.9 | 397 | 81.4 |
Women | 328 | 21.0 | 237 | 22.1 | 91 | 18.7 |
Median age in years (IQR) | 58.1 | (50.7-63.9) | 56.9 | (49.6-63.1) | 60.2 | (54.5-65.4) |
Age groups | ||||||
< 30 years of age | 24 | 1.5 | 20 | 1.9 | 4 | 0.8 |
30-40 years of age | 75 | 4.8 | 68 | 6.3 | 7 | 1.4 |
40-50 years of age | 255 | 16.3 | 194 | 18.1 | 61 | 12.5 |
50-60 years of age | 561 | 35.9 | 392 | 36.5 | 169 | 34.6 |
> 60 years of age | 647 | 41.4 | 400 | 37.2 | 247 | 50.6 |
Country of birtha | ||||||
The Netherlands | 1519 | 97.8 | 1041 | 97.6 | 478 | 98.2 |
Any other country | 35 | 2.3 | 26 | 2.4 | 9 | 1.8 |
Level of educationb | ||||||
Low/intermediate | 780 | 50.3 | 508 | 47.7 | 272 | 56.1 |
High | 770 | 49.7 | 557 | 52.3 | 213 | 43.9 |
B. Health-related characteristics | ||||||
Previous HEV-test for medical reasonsc | ||||||
No | 1368 | 88.4 | 927 | 87.2 | 441 | 90.9 |
Yes | 8 | 0.5 | 6 | 0.6 | 2 | 0.4 |
Unknown | 172 | 11.1 | 130 | 12.2 | 42 | 8.7 |
Health complaints last 2 monthsf | ||||||
Fever | 56 | 3.7 | 39 | 3.7 | 17 | 3.6 |
Nausea | 54 | 3.5 | 41 | 3.9 | 13 | 2.7 |
Diarrhea < 3 times/day | 125 | 8.2 | 83 | 7.9 | 42 | 8.8 |
Stomach ache | 91 | 6.0 | 67 | 6.4 | 24 | 5.0 |
Headache | 282 | 18.4 | 216 | 20.5 | 66 | 13.8 |
Tiredness | 306 | 20.1 | 228 | 21.7 | 78 | 16.4 |
Dark urine | 73 | 4.8 | 52 | 5.9 | 21 | 4.4 |
Itching | 163 | 10.6 | 116 | 11.0 | 47 | 9.8 |
Neurological symptoms | 75 | 4.9 | 51 | 4.9 | 24 | 5.0 |
Underlying diseases last 6 monthsf | ||||||
High blood pressure | 214 | 13.7 | 143 | 13.3 | 71 | 14.5 |
Diabetes | 51 | 3.3 | 30 | 2.8 | 21 | 4.3 |
High cholesterol | 126 | 8.1 | 82 | 7.6 | 44 | 9.0 |
Alcohol consumptiond | ||||||
< =6 drinks per week | 938 | 62.5 | 661 | 64.2 | 277 | 58.7 |
> 7 drinks per week | 564 | 37.6 | 369 | 35.8 | 195 | 41.3 |
Smokinge | ||||||
No, never | 710 | 46.8 | 503 | 48.4 | 207 | 43.4 |
Past smoker | 665 | 43.8 | 445 | 42.8 | 220 | 46.1 |
Current smoker | 142 | 9.4 | 92 | 8.9 | 50 | 10.5 |
Traveling history (lifetime) | ||||||
Asia | 687 | 44.0 | 479 | 44.6 | 208 | 42.6 |
Africa | 528 | 33.8 | 362 | 33.7 | 166 | 34.0 |
North-America | 585 | 37.5 | 410 | 38.2 | 175 | 35.9 |
Central/South-America | 417 | 26.7 | 306 | 28.5 | 111 | 22.8 |
C. Consumption of meat g | ||||||
No, never | 5 | 0.3 | 5 | 0.5 | 0 | 0 |
No, only in the past | 24 | 1.6 | 20 | 1.9 | 4 | 0.8 |
Yes | 1518 | 98.1 | 1036 | 97.6 | 482 | 99.2 |