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Table 3 Independent risk factors associated with long term death in patients admitted with severe infection

From: Risk factors for long-term mortality in patients admitted with severe infection

Variable Total Dead at 5 years Adjusted OR (95% CI)
Model 1 Model 2
Age, mean ± SD, per year 65 ± 20 74 ± 14 1,03
(1.02–1.04)
1,04
(1.03–1.05)
Cancer, n (%) 45 (4) 36 (10) 4.36
(1.65– 11.53)
5.93
(2.26– 15.51)
Chronic haematologic disease, n (%) 59 (6) 35 (9)   2.37
(1.14–4.93)
No comorbidities, n (%) 352 (35) 78 (21) 0.40
(0.26–0.62)
0.45
(0.29–0.69)
Karnofsky Index < 70, n (%) 311 (31) 195 (52) 2.25
(1.48–3.40)
2.32
(1.54–3.50)
Severity of infection, n (%)
 Infection 275 (27) 86 (23)   1.00
  Sepsis 355 (35) 125 (33)   1.15
(0.72–1.83)
 Severe sepsis 292 (29) 116 (31)   1.33
(0.81– 2.17)
 Septic shock 91 (9) 52 (14)   3.77
(1.80– 7.89)
SAPS II, median ± SD, per point 29 ± 13 35 ± 14 1.05
(1.03–1.07)
 
Positive blood cultures, n (%) 151 (15) 70 (19) 1.57
(1.01–2.44)
 
Infection by an ESKAPE pathogen, n (%) 113 (18) 61 (24) 1.61
(1.00–2.60)
1.61
(1.00–2.60)
  1. OR Odds ratio, CI Confidence interval, ESKAPE Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species