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Table 3 Independent risk factors associated with long term death in patients admitted with severe infection

From: Risk factors for long-term mortality in patients admitted with severe infection

Variable

Total

Dead at 5 years

Adjusted OR (95% CI)

Model 1

Model 2

Age, mean ± SD, per year

65 ± 20

74 ± 14

1,03

(1.02–1.04)

1,04

(1.03–1.05)

Cancer, n (%)

45 (4)

36 (10)

4.36

(1.65– 11.53)

5.93

(2.26– 15.51)

Chronic haematologic disease, n (%)

59 (6)

35 (9)

 

2.37

(1.14–4.93)

No comorbidities, n (%)

352 (35)

78 (21)

0.40

(0.26–0.62)

0.45

(0.29–0.69)

Karnofsky Index < 70, n (%)

311 (31)

195 (52)

2.25

(1.48–3.40)

2.32

(1.54–3.50)

Severity of infection, n (%)

 Infection

275 (27)

86 (23)

 

1.00

  Sepsis

355 (35)

125 (33)

 

1.15

(0.72–1.83)

 Severe sepsis

292 (29)

116 (31)

 

1.33

(0.81– 2.17)

 Septic shock

91 (9)

52 (14)

 

3.77

(1.80– 7.89)

SAPS II, median ± SD, per point

29 ± 13

35 ± 14

1.05

(1.03–1.07)

 

Positive blood cultures, n (%)

151 (15)

70 (19)

1.57

(1.01–2.44)

 

Infection by an ESKAPE pathogen, n (%)

113 (18)

61 (24)

1.61

(1.00–2.60)

1.61

(1.00–2.60)

  1. OR Odds ratio, CI Confidence interval, ESKAPE Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species