Bacterial risk factors for treatment failure and relapse among patients with isoniazid resistant tuberculosis

BMC Infectious Diseases

Table 3 Association between drug resistance and bacterial lineage

Lineage^a	Crude OR	95% CI	P-value	Adjusted OR^b	95% CI	P-value
Beijing n = 1017
INH resistant	1.45	1.15–1.81	< 0.001	1.44	1.15–1.81	0.002
MDR	2.59	1.44–4.63	0.001	2.54	1.42–4.57	0.002
Indo-Oceanic n = 406
INH resistant	0.63	0.49–0.83	< 0.001	0.63	0.48–0.83	0.001
MDR	0.37	0.17–0.78	0.009	0.37	0.18–0.79	0.010
Euro-American n = 181
INH resistant	0.88	0.62–1.25	0.477	0.89	0.62–1.26	0.504
MDR	0.36	0.11–1.17	0.091	0.37	0.11–1.19	0.094

^aComparison for each lineage against all other strains. Lineage was indeterminate (mixed lineage, failed PCR or DNA not available) for 106/1710 (6.2%) strains
^bAdjusted for young age (< 35 years of age) and sex
Statistically significant findings are highlighted in bold

ISSN: 1471-2334