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Table 3 Association between drug resistance and bacterial lineage

From: Bacterial risk factors for treatment failure and relapse among patients with isoniazid resistant tuberculosis

Lineagea Drug resistance pattern Crude OR 95% CI P-value Adjusted ORb 95% CI P-value
Beijing n = 1017
 INH resistant 1.45 1.15–1.81 < 0.001 1.44 1.15–1.81 0.002
 MDR 2.59 1.44–4.63 0.001 2.54 1.42–4.57 0.002
Indo-Oceanic n = 406
 INH resistant 0.63 0.49–0.83 < 0.001 0.63 0.48–0.83 0.001
 MDR 0.37 0.17–0.78 0.009 0.37 0.18–0.79 0.010
Euro-American n = 181
 INH resistant 0.88 0.62–1.25 0.477 0.89 0.62–1.26 0.504
 MDR 0.36 0.11–1.17 0.091 0.37 0.11–1.19 0.094
  1. aComparison for each lineage against all other strains. Lineage was indeterminate (mixed lineage, failed PCR or DNA not available) for 106/1710 (6.2%) strains
  2. bAdjusted for young age (< 35 years of age) and sex
  3. Statistically significant findings are highlighted in bold