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Table 5 Pharmacokinetic parameters of streptomycin in the hypoxia and control groups

From: Continuous hypoxia reduces the concentration of streptomycin in the blood

Pharmacokinetic parameters Hypoxia Control
t1/2 67.618 h 69.828 h
AUC (0-t) 30,562.744 mg/L.h 39,512.611 mg/L.h
AUC (0-∞) 30,562.852 mg/L.h 39,512.611 mg/L.h
Ka 5.078/h 0.129/h
Tmax 20 h 20 h
Vz/F 0.234 L/kg 0.093 L/kg
CLz/F 0 L/h/kg 0 L/h/kg
Cmax 177.51 mg/L 310.3 mg/L