Table 5 Factors associated with unsuccessful treatment outcomes among new pulmonary smear-negative tuberculosis patients in Anqing, China, 2005–2013 (n = 8156)
Variables | Total (n = 8156) | Unsuccessful outcomes | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | ||||
Sex | Female | 2266 (27.78) | 112 (4.94) | 1 | |||
Male | 5890 (72.22) | 296 (5.03) | 1.02 (0.81, 1.27) | 0.88 | |||
Age | 15~ 24 | 1237 (15.17) | 36 (2.91) | 1 | 1 | ||
25~ 34 | 714 (8.75) | 28 (3.92) | 1.36 (0.82, 2.25) | 0.23 | 1.34 (0.73, 2.47) | 0.34 | |
35~ 44 | 1189 (14.58) | 43 (3.62) | 1.25 (0.80, 1.96) | 0.33 | 1.22(0.69, 2.16) | 0.50 | |
45~ 54 | 1275 (15.63) | 65 (5.10) | 1.79 (1.18, 2.71) | < 0.001 | 1.79 (1.04, 3.09) | 0.04 | |
55~ 64 | 1744 (21.38) | 87 (4.99) | 1.75 (1.18, 2.60) | < 0.001 | 1.59 (0.93, 2.74) | 0.09 | |
≥65 | 1997 (24.49) | 149 (7.46) | 2.69 (1.86, 3.90) | < 0.001 | 2.57 (1.52, 4.35) | < 0.001 | |
Ethnicity | Han | 8141 (99.82) | 407 (5.00) | 0.74 (0.10, 5.62) | 0.54 | ||
Other | 15 (0.18) | 1 (6.67) | 1 | ||||
Occupation | Student | 607 (7.44) | 19 (3.13) | 1 | |||
Official staff | 166 (2.04) | 12 (7.23) | 2.41 (1.15, 5.08) | 0.02 | |||
Service | 160 (1.96) | 6 (3.75) | 1.21 (0.47, 3.07) | 0.69 | |||
Worker | 683 (8.37) | 28 (4.10) | 1.32 (0.73, 2.39) | 0.36 | |||
Farmer | 5940 (72.83) | 321 (5.40) | 1.77 (1.10, 2.83) | 0.02 | |||
Retired staff | 172 (2.11) | 13 (7.56) | 2.53 (1.22, 5.23) | 0.01 | |||
Unemployment | 140 (1.72) | 4 (2.86) | 0.91 (0.31, 2.72) | 0.87 | |||
Other | 388 (3.53) | 5 (1.74) | 0.55 (0.20, 1.48) | 0.23 | |||
Way of discovering patients | Health examination | 165 (2.02) | 5 (3.03) | 1 | |||
Contact examination | 40 (0.49) | 2 (5.00) | 1.68 (0.32, 9.01) | 0.54 | |||
Clinic visit due to symptoms | 3548 (43.50) | 175 (4.93) | 1.66 (0.67, 4.10) | 0.27 | |||
Recommended due to symptoms | 30 (0.37) | 1 (3.33) | 1.10 (0.12, 9.79) | 0.93 | |||
Referral | 3793 (46.51) | 197 (5.19) | 1.75 (0.71, 4.32) | 0.22 | |||
Tracing | 559 (6.85) | 27 (4.83) | 1.62 (0.62, 4.29) | 0.33 | |||
Other | 21 (0.26) | 1 (4.76) | 1.60 (0.18, 14.39) | 0.68 | |||
Treatment management models | Self-medication | 30 (0.37) | 4 (13.33) | 2.84 (0.96, 8.41) | 0.06 | 2.95 (0.98, 8.90) | 0.055 |
Full-course supervision | 1049 (12.86) | 54 (5.15) | 1 | 1 | |||
Full-course management | 513 (6.29) | 59(11.50) | 2.40 (1.63, 3.52) | < 0.001 | 2.54 (1.70, 3.81) | < 0.001 | |
Supervision in intensive phase | 6564 (80.48) | 291 (4.43) | 0.86 (0.63, 1.15) | 0.30 | 0.95 (0.70, 1.30) | 0.76 | |
X-Ray | Normal | 122 (1.50) | 0 | – | – | < 0.01 (< 0.01, > 999.99) | 0.96 |
Abnormal | 8000 (98.09) | 402 (5.03) | 1 | 1 | |||
Unchecked | 34 (0.42) | 6 (17.65) | 4.00(1.67–10.00) | 0.002 | 3.77 (1.50, 9.45) | 0.005 | |
Cavity | Yes | 683 (8.37) | 32 (4.69) | 0.93 (0.64, 1.34) | 0.69 | ||
No | 7473 (91.63) | 376 (5.03) | 1 | ||||
Miliary shadow | Yes | 70 (0.86) | 8 (11.43) | 2.48 (1.18, 5.21) | 0.02 | 2.43 (1.12, 5.25) | 0.02 |
No | 8086 (99.14) | 400 (4.95) | 1 | 1 | |||
Regimen | Regimen 1a | 5111 (62.67) | 278 (5.44) | 1 | |||
Regimen 2b | 3045 (37.33) | 130 (4.27) | 0.78 (0.63, 0.96) | 0.02 | |||
Total delay | ≤13 | 2047 (25.10) | 94 (4.59) | 1 | 1 | ||
13~ 27 | 2054 (25.18) | 80 (3.89) | 0.84 (0.62, 1.14) | 0.27 | 0.84 (0.62, 1.14) | 0.27 | |
27~ 51 | 2046 (25.09) | 100 (4.89) | 1.07 (0.80, 1.43) | 0.66 | 1.05(0.78, 1.41) | 0.74 | |
> 51 | 2009 (24.63) | 134 (6.67) | 1.49 (1.13, 1.95) | 0.004 | 1.40 (1.06, 1.85) | 0.019 | |