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Table 2 Sputum smear and LJ culture bacillary load by TB-LAMP test result and setting

From: Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda

 

TB-LAMP

P-value

Site

P-value

Positive, N = 49 (%)

Negative, N = 184 (%)

Hospital, N = 126 (%)

Health Centre, N = 107 (%)

LJ MTB culture quantification (Colonies)

 Greater than 20 (N = 57)

43 (87.8)

14 (7.6)

0.000

26 (20.6)

31 (29)

0.061

 10-20 (N = 2)

00

02 (1.1)

 

00

02 (1.87)

 

 Less than 10 (N = 1)

01 (2.0)

00

 

00

01 (0.9)

 

Negative/contaminated (N = 173)

05 (10.2)

168 (91.3)

 

100 (79.4)

73 (68.2)

 

Smear microscopy AFB quantification

 3+

14 (28.6)

00

0.000

07 (5.6)

07 (6.0)

0.867

 2+

13 (26.5)

00

 

06 (4.8)

07 (6.5)

 

 1+

06 (12.2)

07 (3.8)

 

08 (6.4)

05 (4.7)

 

 Scanty

03 (6.1)

00

 

01 (0.8)

02 (1.9)

 

Negative

13 (26.5)

177 (96.2)

 

104 (82.5)

86 (80.4)

 
  1. AFB Acid Fast Bacilli, LJ Lowenstein-Jensen