Fig. 5
From: IL-10+ NK and TGF-β+ NK cells play negative regulatory roles in HIV infection
Effect of rIL-10 and rTGF-β on CD107a expression in NK cells
PBMCs were incubated with rIL-10 or rTGF-β and CD107a expression by NK cells evaluated. Representative flow-cytometry plots demonstrated the effect of rIL-10 or rTGF-β on CD107a expression in NK cells (a). CD107a expression by NK cells was inhibited by different concentrations of rIL-10 (b) or rTGF-β (c). Fold-change in CD107a expression by NK cells was synergistically inhibited by rIL-10 and rTGF-β (d). Fold-change of CD107a expression = (percentage CD107a expression in untreated controls − percentage of CD107a expression after treatment with rIL-10 and/or rTGF-β)/percentage of CD107a expression in untreated controls