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Table 2 Molecular characteristics of the 14 mcr-1-positive E. coli strains

From: Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong

Subject Sequence Type Plasmid Replicons Virulence Genes Acquired Resistance Genes
1 442 (Achtman) Unknown (Pasteur) IncI1 cma, iroN, iss, lpfA aadA1, aadA2, bla TEM-1B , dfrA12, mcr-1 , QnrS1, sul3, tet(A),
2 Unknown (Achtman) 201 (Pasteur) IncX4, IncP1 astA, iss, lpfA, mchF, tsh aadA1, aadA2, dfrA12, mcr-1 (‘R’ at nt. 1263), sul3, tet(A)
3 88 (Achtman) 66 (Pasteur) Not detected cma, iroN, iss, lpfA aadA5, mcr-1 , mph(A), strA, strB, sul1
4 Unknown (Achtman) Unknown (Pasteur) IncX4 iss aadA1, aadA2, bla TEM-1B , mcr-1 (27C>T), sul3, tet(B)
5 Unknown (Achtman) 1716 (Pasteur) IncI1 astA aac(6’)Ib-cr, aadA5, ARR-3, dfrA17, bla OXA-1 , mcr-1 , oqxA, oqxB, QnrS2
6 155 (Achtman) 21 (Pasteur) IncN lpfA aadA1, aadA2, aph(3’)-Ia, bla TEM-1B , dfrA12, mcr-1 , mph(A), oqxA, oqxB, sul2, sul3
7 10 (Achtman) 2 (Pasteur) IncN Not detected aadA1, aadA2, aph(3’)-Ia, bla TEM-1B , dfrA12, mcr-1 , mph(A), sul2, sul3
8 34 (Achtman) 638 (Pasteur) Not detected Not detected mcr-1
9 226 (Achtman) 486 (Pasteur) IncR, IncX4 Not detected mcr-1 , strA, strB, tet(B)
10 5995 (Achtman) Unknown (Pasteur) IncQ1 Not detected aph(3’)-Ia, bla TEM-1B , mcr-1 , strA, strB
11 95 (Achtman) 1 (Pasteur) IncI1, IncI2, IncQ1 iss, sfaS aph(3’)-Ia, bla TEM-1B , dfrA17, mcr-1 , oqxA, oqxB, strA, strB, sul2, tet(B)
12 48 (Achtman) Unknown (Pasteur) Not detected Not detected aadA2, blaCTX-M-9-like gene, dfrA12, mcr-1, sul3
13 48 (Achtman) Unknown (Pasteur) IncN, IncHI2 Not detected aadA1, blaCTX-M-9-like gene, dfrA12, fosA3, mcr-1, QnrS1, sul1, sul3
14 746 (Achtman) Unknown (Pasteur) Not detected astA aadA1, aadA2, aph(3’)-Ia, dfrA12, mcr-1 , oqxA, oqxB, QnrS1, sul3