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Table 1 Subject details and antibiotic susceptibilities of the 14 mcr-1-positive E. coli strains

From: Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong

Subject Age/Year Subject typea ESBLb producer? Carbapenem susceptible? PB MICc (μg/mL) PE MICd (μg/mL) PE MICe (μg/mL) Non-susceptible antibioticsg (based on CLSI guidelines)
1f 45 OP No Yes 8 4 8 AMR, CFI, SXTR
2 54 HA No Yes 8 2 8 SXTR
3 42 IP No Yes 8 4 8 CFI, MII, SXTR
4 54 HA No Yes 12 4 8 AMR, AMCI, ANI, MIR, SXTR
5 2 IP No Yes 4 4 4 AMR, AMCR, ANR, CFR, CIPR, CNR, CXMR, LEVI, SXTI, TIMR, TOBR, TZPR
6 45 HA No Yes 8 4 8 AMR, AMCI, CIPR, CNR, CXMI, LEVR, SXTR, TIMI, TOBR
7 43 HA No Yes 8 4 4 AMR, AMCI, CFR, CIPI, CXMI, LEVI, MII, SXTR, TIMI, TZPR
8 31 HA No Yes 12 4 > 16 All susceptible
9 52 HA No Yes 4 2 4 CFI, CXMI
10f 1 IP No Yes 6 4 8 AMR, ANI, CFR, CXMI, MII, TOBI
11 58 HA No Yes 8 4 8 AMR, SXTR
12 7 OP Yes Yes 12 4 4 AMR, AMCR, CAZR, CFR, CTXR, CXMR, FEPR, SXTR
13 49 HA Yes Yes 8 4 4 AMR, AMCR, ANI, CAZR, CFR, CIPR, CNR, CTXR, CXMR, FEPR, LEVI, SXTR, TOBR
14 55 HA No Yes 6 2 2 AMR, CFR, CIPI, CXMI, MII, SXTR
  1. aOP outpatients, HA clients coming for health assessment, IP inpatients
  2. bESBL, extended-spectrum β-lactamase
  3. cPB MIC, Polymyxin B minimum inhibitory concentration by Etest
  4. dPE MIC, Polymyxin E (colistin) minimum inhibitory concentration by broth microdilution (SensiTest Colistin)
  5. ePE MIC, Polymyxin E (colistin) minimum inhibitory concentration by Vitek® 2 AST N-338
  6. fThe subjects had received antibiotic treatment other than colistin prior to fecal specimen collection
  7. gI intermediate, R resistant, AM ampicillin, AMC amoxicillin-clavulanate, AN amikacin, CAZ ceftazidime, CF cephalothin, CIP ciprofloxacin, CN gentamicin, CTX cefotaxime, CXM cefuroxime, FEP cefepime, LEV levofloxacin, MI minocycline, SXT trimethoprim/sulfamethoxazole, TIM ticarcillin-clavulanate, TOB tobramycin, TZP piperacillin-tazobactam