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Table 1 Distribution of characteristics of TB patients according to their M. tuberculosis isolates’ IS6110 RFLP cluster status

From: Risk factors associated with cluster size of Mycobacterium tuberculosis (Mtb) of different RFLP lineages in Brazil

Characteristics Categories All patients Cluster Unique Patterns (PU) Odds Ratio
   N = 959 (%) N = 461 (%) N = 498 (%) (95% CI)d
Demographic
 Age (years old) < 20 years 100 (11.0) 62 (14.4) 38 (8.0) 1
21–30 years 247 (27.3) 115 (26.7) 132 (27.9) 0.53 (0.33–0.85)
31–40 years 220 (24.4) 100 (23.2) 120 (25.4) 0.51 (0.31–0.82)
41–50 years 194 (21.5) 93 (21.6) 101 (21.4) 0.56 (0.34–0.92)
> 50 years 143 (15.8) 61 (14.1) 82 (17.3) 0.45 (0.27–0.76)
 Gender Female 287 (30.0) 134 (29.0) 153 (31.0) 1
Male 672 (70.0) 327 (71.0) 345 (69.0) 1.08 (0.82–1.42)
 Race White 190 (30.0) 90 (29.0) 100 (31.0) 1
Black 119 (19.0) 64 (20.0) 55 (17.0) 1.29 (0.81–2.04)
Othersa 323 (51.0) 158 (51.0) 165 (52.0) 1.06 (0.74–1.52)
 Schooling (years) ≤4 years 106 (21.0) 50 (21.0) 56 (22.0) 1
5 to 8 years 304 (61.0) 150 (62.0) 154 (59.0) 1.09 (0.70–1.69)
≥ 8 years 90 (18.0) 41 (17.0) 49 (19.0) 0.93 (0.53–1.64)
 Metropolitan Area Vitoria 583 (61.0) 290 (63.0) 293 (59.0) 1
Vila Velha 89 (9.0) 40 (9.0) 49 (10.0) 0.82 (0.52–1.29)
Cariacica 120 (13.0) 60 (13.0) 60 (12.0) 1.01 (0.68–1.49)
Serra 123 (13.0) 53 (11.0) 70 (14.0) 0.76 (0.51–1.13)
Outros 44 (5.0) 18 (4.0) 26 (5.0) 0.70 (0.37–1.30)
Clinical
 X-Ray No 46 (6.0) 26 (8.0) 20 (5.0) 1
Yes 667 (94.0) 318 (92.0) 349 (95.0) 0.99 (0.96–1.03)
 TB Presentation PTBb 779 (81.0) 390 (85.0) 389 (78.0) 1
EPTB 111 (12.0) 40 (9.0) 71 (14.0) 0.56 (0.37–0.84)
PTB + EPTB 69 (7.0) 31 (7.0) 38 (8.0) 0.81 (0.49–1.33)
 AFB Smears Results Negative 147 (15.0) 65 (14.0) 82 (17.0) 1
Positivec 802 (85.0) 389 (86.0) 41 3 (83.0) 1.18 (0.83–1.69)
Molecular
 Spoligotyping Non LAM 412 (48.0) 195 (50.0) 217 (46.0) 1
LAM 448 (52.0) 193 (50.0) 255 (54.0) 0.84 (0.64–1.10)
 RDRio Genotype Non - RDRio 552 (60.0) 253 (58.0) 299 (62.0) 1
RDRio 369 (40.0) 185 (42.0) 184 (38.0) 1.07 (0.99–1.15)
  1. a – Based on the SINAN response field for skin color
  2. b– PTB = pulmonary TB, EPTB = extrapulmonary TB
  3. c- All smear positive results were stratified as + 1 (10–99 AFB/100 fields), + 2 (1–10 AFB/field) and + 3 (> AFB/field)
  4. d – Crude odds ratio from univariate logistic regression. CI, confidence interval