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Table 5 Pathogens identified in 55 children with laboratory-confirmed CNS infection

From: The aetiologies of central nervous system infections in hospitalised Cambodian children

Pathogen, n (%) 1-11 m (n = 11) 1-4y (n = 20) 5-15y (n = 24) Overall (n = 55) P-value
Enterovirusa 2 (18.2) 8 (40.0) 11 (45.8) 21 (38.3) 0.1
Japanese encephalitis virus 1 (9.1) 7 (35.0) 9 (37.5) 17 (31.0) 0.1
Streptococcus pneumoniae 3 (27.2) 3 (15.0) 1 (4.2) 7 (12.7) 0.05
Escherichia coli 2 (18.2) 0 (0) 0 (0) 2 (3.6)
Mumps virus 0 (0) 0 (0) 2 (8.3) 2 (3.6)
Neisseria meningitidis 2 (18.2) 0 (0) 0 (0) 2 (3.6)
Cryptococcus neoformans 0 (0) 0 (0) 1 (4.2) 1 (1.8)
Haemophilus influenzae type b 1 (9.1) 0 (0) 0 (0) 1 (1.8)
Herpes simplex virus 0 (0) 1 (5.0) 0 (0) 1 (1.8)
Staphylococcus aureus 0 (0) 1 (5.0) 0 (0) 1 (1.8)
Parechovirus 0 (0) 0 (0) 0 (0) 0 (0)
Varicella zoster virus 0 (0) 0 (0) 0 (0) 0 (0)
  1. aAnother 4 children (all 5-15y) were enterovirus positive on deep sequencing (not part of the core diagnostic strategy)