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Table 1 Sensitivities and specificities of four individual antigens and the multiple-antigen combination set with serum from LTBI individuals and healthy controls

From: ORFeome-based identification of biomarkers for serodiagnosis of Mycobacterium tuberculosis latent infection

Rv. Latent TB (N = 62) Sensitivity (%, 95% CI) Healthy controls (N = 32) Specificity (%, 95% CI)
Specific
Positive
Nonspecific
Positive
Negative Positive Negative
Rv1146 2 20 40 35.5 (24.0–48.7) 1 31 96.9 (82.0–99.8)
Rv1977 6 21 35 43.6 (31.2–56.7) 1 31 96.9 (82.0–99.8)
Rv3090 4 16 42 32.3 (21.3–45.5) 1 31 96.9 (82.0–99.8)
Rv3206c 3 19 40 35.5 (24.0–48.7) 2 30 93.8 (77.8–98.9)
Multiple 41   21 66.1 (52.9–77.4) 4 28 87.5 (70.1–95.1)
  1. Abbreviation: CI confidence intervals. Specific Positive: serum samples which recognized only one of four antigens; Nonspecific Positive: serum samples which reacted with various antigens